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F5396

Sigma-Aldrich

Fenbendazole

≥98%

Sinónimos:

Methyl 5-(phenylthio)-2-benzimidazolecarbamate

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5 G
73,10 €
100 G
165,00 €

73,10 €

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5 G
73,10 €
100 G
165,00 €

About This Item

Fórmula empírica (notación de Hill):
C15H13N3O2S
Número de CAS:
43210-67-9
Peso molecular:
299.35
Beilstein:
759077
Número CE:
256-145-7
Número MDL:
MFCD00144301
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
57654186
NACRES:
NA.22

73,10 €

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Nivel de calidad

200

Ensayo

≥98%

cadena SMILES

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

Clave InChI

HDDSHPAODJUKPD-UHFFFAOYSA-N

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Descripción general

Fenbendazole also known as Methyl 5-(phenylthio)-2-benzimidazolecarbamate, is a benzimidazole anthelmintic and antiprotozoal agent.

Aplicación


  • Fenbendazole in Veterinary Medicine: Investigated for efficacy against coccidicidal fungi in avian species, demonstrating broad-spectrum antiparasitic potential. Additionally, its environmental impact and pharmacokinetics reveal insights for sustainable agricultural practices and disease vector control. (Lozano et al., 2024), (Hachgenei et al., 2024), (Durden et al., 2023).

  • Food safety and allergen detection: Fenbendazole′s implications in food safety are explored through quantitative PCR methods for detecting allergenic species in foods, underscoring the importance of accurate detection techniques in food industry compliance and safety standards (Costa et al., 2023).

  • Analysis of antibiotic and anthelmintic residues: The occurrence and exposure evaluation of Fenbendazole residues in cow milk in China is studied, emphasizing the need for rigorous monitoring of food products to ensure public health safety (Chang et al., 2023).


Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palabra de señalización

Warning

Frases de peligro

H361fd,H373,H410

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

Órganos de actuación

Liver,lymph node,Stomach,Nervous system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000328425
0000328477
0000284710
0000268207
0000292170

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Niels C Kyvsgaard et al.
Veterinary parasitology, 181(2-4), 248-254 (2011-05-17)
Horses, mules and donkeys are indispensable farming and working animals in many developing countries, and their health status is important to the farmers. Strongyle parasites are ubiquitous in grazing horses world-wide and are known to constitute a threat to equine
Nilambra Dogra et al.
The Journal of biological chemistry, 287(36), 30625-30640 (2012-06-30)
In recent years, there has been a great deal of interest in proteasome inhibitors as a novel class of anticancer drugs. We report that fenbendazole (FZ) (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate) exhibits a potent growth-inhibitory activity against cancer cell lines but not normal
C Chassaing et al.
Journal of medicinal chemistry, 51(5), 1111-1114 (2008-02-15)
Highly water-soluble prodrugs 1a- g of anthelmintic benzimidazole carbamates 2a- g were synthesized. These prodrugs combine high aqueous solubility and stability with high lability in the presence of alkaline phosphatases. The veterinary utility of 1a was shown by a pharmacodynamic
Moreno Rossi et al.
Journal of feline medicine and surgery, 13(10), 793-795 (2011-08-13)
An 8-month-old owned European cat showing abdominal pain, fever, distended painful bladder and urinary blockage was presented. Intravenous fluids were immediately administered and, after sedation, a urinary catheter was applied. Blood and urine analysis revealed cystitis and a moderate-to-severe degree
Aileen Adam et al.
Veterinary parasitology, 177(3-4), 383-386 (2011-01-18)
On red grouse estates in the UK the nematode parasite Trichostrongylus tenuis is often controlled by application of grit medicated with the anthelmintic fenbendazole (FBZ). To date, assessment of the efficacy has been inhibited by the inability to quantify uptake
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Preguntas

1–2 de 2 Preguntas  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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