419508

Boron tribromide

ReagentPlus^®, ≥99%

• Sinónimos: Tribromoboron
• Fórmula empírica (notación de Hill): BBr₃
• Número de CAS: 10294-33-4
• Peso molecular: 250.52
• Número CE: 233-657-9
• Número MDL: MFCD00011312
• Código UNSPSC: 12352101
• ID de la sustancia en PubChem: 24866111
• NACRES: NA.22
• Ensayo: ≥99%

Propiedades

• densidad de vapor: 8.6 (vs air)
• Nivel de calidad: 200
• presión de vapor: 40 mmHg ( 14 °C)
• Línea del producto: ReagentPlus^®
• Ensayo: ≥99%
• color: colorless to amber
• bp: ~90 °C (lit.)
• mp: −46 °C (lit.)
• densidad: 2.60 g/mL at 20 °C (lit.)
• cadena SMILES: BrB(Br)Br
• InChI: 1S/BBr3/c2-1(3)4
• Clave InChI: ILAHWRKJUDSMFH-UHFFFAOYSA-N

Descripción

Descripción general

Boron tribromide is a strong Lewis acid generally employed in the deprotection of -OH and -NH groups. It is a moisture-sensitive liquid, which is also used to cleave esters or ethers into alkyl bromides.

Aplicación

Reactant for preparation of:

• Drug intermediate 6-nitro-L-DOPA
• Luminescent polystyrene derivatives with sterically protected carbazolylborane moieties
• High-quality boron-doped graphene via Wurtz-type reductive coupling reaction
• Mercapto-(+)-methamphetamine haptens for synthesis of (+)-methamphetamine conjugate vaccines with improved epitope densities
• Micrometer-sized organic molecule-DNA hybrid structures
• Borane complexes via electrophilic aromatic borylation reactions
• A 5-HT2C receptor agonist
• Biphenyl-derivatives possessing tertiary amino groups as β-secretase(BACE1) inhibitors for the treatment of Alzheimer′s disease
• A highly near-IR region fluorescent p-extended boron aza-dipyrromethene moiety unit
• Tetrahydroisoquinoline derivatives via intramolecular cyclization of methoxy-substituted N-phenethylimides

Used to cleave aryl methyl ethers in a synthesis of a benzopyranobenzopyran from a coumarin scaffold.

Información legal

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H300 + H330,H314
• Consejos de prudencia: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1A
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter