412422

PAMAM dendrimer, ethylenediamine core, generation 3.0 solution

20 wt. % in methanol

• Sinónimos: Starburst PAMAM-G 3
• Fórmula lineal: [NH₂(CH₂)₂NH₂]:(G=3);dendri PAMAM(NH₂)₃₂
• Número de CAS: 153891-46-4
• Peso molecular: 6908.84
• Número MDL: MFCD00197936
• Código UNSPSC: 12162002
• NACRES: NA.23

Propiedades

• descripción: amino surface groups
• Nivel de calidad: 100
• Formulario: liquid
• mol peso: generation 3.0
• Características: core type ethylenediamine core (2-carbon core)
• concentración: 20 wt. % in methanol
• nº de grupos superficiales: 32
• índice de refracción: n20/D 1.367
• bp: 64.7 °C
• densidad: 0.863 g/mL at 25 °C
• temp. de almacenamiento: 2-8°C

Descripción

Descripción general

PAMAM dendrimer is a symmetrical polymer with a large number of terminal groups that can easily bind to biomolecules due to their biocompatibility and affinity. These dendrimers have a multivalent surface that contains envelopes and various active sites at the core with the attached dendrons. They are highly branched nanoscale polymers that are extensively used in the field of biomedicine for targeted drug delivery.[1]

Aplicación

PAMAM dendrimers can be used as transfection agents for the delivery of nucleic acids. For example, it can be used in the pulmonary delivery of siRNA directed against tumor necrosis factor (TNF).[2]

Forma física

Contains 32 surface primary amino groups

Información legal

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Información de seguridad

• Pictogramas: GHS02,GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225,H301 + H311 + H331,H370
• Consejos de prudencia: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órganos de actuación: Eyes,Central nervous system
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 51.8 °F - closed cup
• Punto de inflamabilidad (°C): 11 °C - closed cup