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Merck

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Sinónimos:
5-HT4, 5-HT4R
Especie:
Human HTR4 (3360), Mouse Htr4 (15562), Rat Htr4 (25324), Horse HTR4 (100034053), domestic cat HTR4 (101088723), sheep HTR4 (101117928), cow HTR4 (317708), domestic guinea pig Htr4 (100135548), chicken HTR4 (416150), dog HTR4 (489198)
ID UniProtKB:
Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73
ID del gen:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
SML1504
Tegaserod maleate, ≥98% (HPLC),
Especie
human
32473
Metoclopramide, VETRANAL®, analytical standard,
Especie
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Especie
human
M0763
Metoclopramide hydrochloride, solid,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
S3313
SB-204070 hydrochloride, solid, ≥97% (HPLC),
Especie
human
M7319
ML 10302, ≥98%, solid,
Especie
rat
G5918
GR 113808, ≥98% (HPLC), solid,
Especie
rat, human
32473
Metoclopramide, VETRANAL®, analytical standard,
Especie
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4501480
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot
HPA040591
Anti-HTR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB2101109
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, human, rabbit
Aplicación
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Especie
human
Z101
Zimelidine dihydrochloride, solid,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Especie
human
F132
Fluoxetina hydrochloride, solid,
Especie
human
R0875
Reserpine, ,
Especie
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU070651
MISSION® esiRNA, targeting human HTR4,
Especie
human