SAB4501894

Anti-MMP-7 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: MMP-7, Matrilysin, Matrix metalloproteinase-7, Pump-1 protease, Uterine metalloproteinase
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 29 kDa
• reactividad de especies: human, mouse, rat
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: P09237
• Nº de acceso UniProt: P09237
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MMP7(4316)

Descripción

Descripción general

Anti-MMP-7 Antibody detects endogenous levels of total MMP-7 protein.

Matrix metalloproteinase-7 (MMP7) is also termed as matrilysin. It is located on human chromosome 11q21-->q22. It belongs to the MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human MMP-7.

Immunogen Range: 218-267

Aplicación

Anti-MMP-7, C-Terminal antibody has been used in immunofluorescence.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

Acciones bioquímicas o fisiológicas

Overexpression of matrix metalloproteinase-7 (MMP7) is observed in various cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. It is essential for the development of tumor in the absence of PKP3 (plakophilin3).

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable