L9507
Lactoferrin from bovine milk
≥85% (SDS-PAGE)
Synonyme(s) :
Bos d LF, Lactotransferrin
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About This Item
Produits recommandés
Source biologique
bovine milk
Niveau de qualité
Pureté
≥85% (SDS-PAGE)
Forme
powder
Poids mol.
~87 kDa
Technique(s)
fractionation: suitable
Solubilité
H2O: soluble 10 mg/mL
Numéro d'accès UniProt
Température de stockage
2-8°C
Informations sur le gène
cow ... LTF(280846)
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Application
Lactoferrin was used in the fractionation of lactoperoxidase and lactoferrin from bovine whey using a cation exchange membrane. It was used in the determination of lactoferrin and immunoglobulin G in animal milks by new immunosensors.
Actions biochimiques/physiologiques
Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
Certificats d'analyse (COA)
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Les clients ont également consulté
Víctor A Solarte et al.
BioMed research international, 2015, 630179-630179 (2015-11-27)
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Mona M Abdel-Wahab et al.
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The present study was carried out to investigate the effects of dietary bovine lactoferrin (BLF) or chitosan nanoparticles (CHN) alone or in combinations on serum biochemical indices, antioxidative capacity, transcriptomic responses, non-specific immunity, and resistance of Nile tilapia (Oreochromis niloticus)
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PeerJ, 9, e11072-e11072 (2021-06-17)
Colorectal cancer is a common cause of death with few available therapeutic strategies, and the preventative complexes in adjunctive therapy are urgently needed. Increasing evidences have shown that natural ingredients, including lactoferrin, oleic acid, docosahexaenoic acid (DHA) and linolenic acid
O Oyen et al.
FEBS letters, 229(2), 391-394 (1988-03-14)
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