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C4654

Sigma-Aldrich

Cytidine

BioReagent, suitable for cell culture, powder, ≥99%

Synonyme(s) :

Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside

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About This Item

Formule empirique (notation de Hill):
C9H13N3O5
Numéro CAS:
Poids moléculaire :
243.22
Beilstein:
89173
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352207
ID de substance PubChem :
Nomenclature NACRES :
NA.75
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Source biologique

synthetic

Niveau de qualité

Gamme de produits

BioReagent

Essai

≥99%

Forme

powder

Technique(s)

cell culture | mammalian: suitable

Pf

210-220 °C (dec.) (lit.)

Solubilité

H2O: 50 mg/mL

Chaîne SMILES 

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

InChI

1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1

Clé InChI

UHDGCWIWMRVCDJ-XVFCMESISA-N

Informations sur le gène

mouse ... Uck1(22245)

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Description générale

Cytidine is a nucleoside molecule. It is formed when cytosine is attached to a ribose ring through a β-N1-glycosidic bond.[1]

Application

Cytidine has been used as a component to prepare ribonucleoside stock solution to assess its effects on the anaerobic growth of several Bacillus mojavensis strains.[2]
Cytidine has been used as a non-essential aminoacid component of minimal essential medium (MEM) to analyse interspecies somatic cell nucleus transfer (iSCNT)-derived blastocysts.[3] It has also been used as a supplement in the culture medium of HeLa cells, to study the effects of cytidine addition on rods and rings (RR) induced by glutamine deprivation.[4]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Filippo M Cernilogar et al.
Nucleic acids research, 47(17), 9069-9086 (2019-07-28)
Pioneer transcription factors (PTF) can recognize their binding sites on nucleosomal DNA and trigger chromatin opening for recruitment of other non-pioneer transcription factors. However, critical properties of PTFs are still poorly understood, such as how these transcription factors selectively recognize
G P Gerrits et al.
Clinical chemistry, 34(7), 1439-1442 (1988-07-01)
Disturbances in the metabolism of purines and pyrimidines in neurologically affected patients can be reflected by aberrant concentrations of nucleosides and nucleobases in cerebrospinal fluid (CSF). However, normal values, especially for children at different ages, are lacking. We collected 1000
Koji Hayakawa et al.
The Journal of biological chemistry, 288(24), 17099-17110 (2013-04-30)
The orexin system plays a central role in the integration of sleep/wake and feeding behaviors in a broad spectrum of neural-metabolic physiology. Orexin-A and orexin-B are produced by the cleavage of prepro-orexin, which is encoded on the Hcrt gene. To
Beata Brozek-Pluska et al.
International journal of molecular sciences, 20(14) (2019-07-13)
Noninvasive Raman imaging of non-fixed and unstained human colon tissues based on vibrational properties of noncancerous and cancerous samples can effectively enable the differentiation between noncancerous and tumor tissues. This work aimed to evaluate the biochemical characteristics of colon cancer
Joana Rocha-Pereira et al.
Journal of virology, 87(21), 11798-11805 (2013-08-30)
Human noroviruses are a major cause of food-borne illness, accountable for 50% of all-etiologies outbreaks of acute gastroenteritis (in both developing and developed countries). There is no vaccine or antiviral drug for the prophylaxis or treatment of norovirus-induced gastroenteritis. We

Questions

1–3 of 3 Questions  
  1. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  2. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  3. How do I dissolve Product No. C4654, Cytidine?

    1 answer
    1. The product is tested for solubility in water at 50 mg/mL.  It may be soluble at higher concentrations as well.  Solutions of cytidine are clear or can be faint yellow in color.

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