C2374

Cyclo-Gly-Pro

≥98% (GC/HPLC)

• Synonyme(s) : (S)-3,6-Dioxohexahydropyrrolo[1,2-a]pyrazine, Glycyl-L-proline lactam, cyclo-GP, cyclo-Glycyl-L-Proline, cyclo-L-prolylglycine
• Formule empirique (notation de Hill) : C₇H₁₀N₂O₂
• Numéro CAS: 3705-27-9
• Poids moléculaire : 154.17
• NACRES: NA.32
• PubChem Substance ID: 329774997
• UNSPSC Code: 12352200
• MDL number: MFCD01083707

Propriétés

• Quality Segment: 100
• assay: ≥98% (GC/HPLC)
• form: powder
• solubility: DMSO: >10 mg/mL
• storage temp.: −20°C
• SMILES string: O=C1CNC(=O)C2CCCN12
• InChI: 1S/C7H10N2O2/c10-6-4-8-7(11)5-2-1-3-9(5)6/h5H,1-4H2,(H,8,11)
• InChI key: OWOHLURDBZHNGG-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Cyclo-Gly-Pro is a neuro-protective compound, an endogenous diketopiperazine, which enhances memory. In the animal model of PD, the compound improved functional recovery when administered after the onset of dyskinesia. It appears that the compound recovery function may result from non-proliferative neurogenesis that results from the inhibition of apoptosis of stem cells and/or the promotion of neuronal-orientated proliferation in the SVZ (subventricular zone).

Cyclo-Gly-Pro is a neuro-protective compound.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable