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Key Documents

937274

Sigma-Aldrich

Poly(propylene sulfide)

new

average Mw 15000

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About This Item

Formule linéaire :
(C3H6S)n
Numéro CAS:
Code UNSPSC :
12352142

Agence

suitable for controlled release

Niveau de qualité

Forme

viscous liquid

Poids mol.

average Mw 15000

Couleur

colorless

Application(s)

advanced drug delivery (tissue engineering, medical devices)

Température de stockage

2-8°C

Description générale

Poly(propylene sulfide) (PPS) is a thermoplastic polymer that has shown potential for use in various biomedical applications due to its biocompatibility, biodegradability, and tunable mechanical and chemical properties.

Application

One promising application of PPS is in drug delivery. PPS nanoparticles can be synthesized and loaded with drugs, providing sustained release and targeted delivery to specific tissues or cells. PPS also has good stability in biological environments, which is important for maintaining drug efficacy during storage and delivery.



PPS has also been explored as a material for tissue engineering. Its biocompatibility and ability to be tailored for specific mechanical and chemical properties make it a potentially useful scaffold material for various tissue types, including bone and cartilage. PPS has also been shown to support cell attachment and growth in vitro.

In addition to drug delivery and tissue engineering, PPS has also been investigated for use in medical devices such as catheters and sutures. Its chemical resistance and low toxicity make it a potential alternative to traditional materials like silicone and nylon. Overall, PPS has shown promise for various biomedical applications, and ongoing research is exploring its potential in areas such as wound healing, cancer therapy, and regenerative medicine.

Caractéristiques et avantages

  • Biocompatible
  • Biodegradable
  • Tunable mechanical and chemical properties
  • Ideal for sustained release and targeted delivery
  • Chemically resisitant and low toxicity

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles
Reddy T S, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 112, 26-34 (2006)
Accelerated wound healing by injectable star poly(ethylene glycol)-b-poly(propylene sulfide) scaffolds loaded with poorly water-soluble drugs
Zhu S, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 282, 156-165 (2018)
Extracellular matrix binding mixed micelles for drug delivery applications
O'Neil P N, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 137, 146-151 (2009)

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