X4002

Xanthin

BioUltra, ≥99%

• Synonym(e): 2,6-Dihydroxy-purin
• Empirische Formel (Hill-System): C₅H₄N₄O₂
• CAS-Nummer: 69-89-6
• Molekulargewicht: 152.11
• Beilstein: 8733
• EG-Nummer: 200-718-6
• MDL-Nummer: MFCD00078453
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24902144
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Produktlinie: BioUltra
• Assay: ≥99%
• Form: powder
• Verunreinigungen: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter
• Glührückstand: ≤0.1%
• Löslichkeit: 1 M NaOH: 0.1 M, clear, colorless to light yellow
• Anionenspuren: sulfate (SO₄^2-): <0.05%
• Kationenspuren: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.005%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES String: O=C1NC(=O)c2nc[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
• InChIKey: LRFVTYWOQMYALW-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:

• Guanine deamination by guanine deaminase
• Hypoxanthine conversion by xanthine oxidoreductase

Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.

Anwendung

Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity.[1][2] It has also been used in the following systems:

• yeast culture[3]
• human cell line culture
• recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

Biochem./physiol. Wirkung

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.

Leistungsmerkmale und Vorteile

• Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
• Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves