This product is sourced from rice as stated on the product detail page.
T0452
D-α-Tocotrienol
from rice, ≥75% (GC)
Synonym(e):
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol
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Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C29H44O2
CAS-Nummer:
Molekulargewicht:
424.66
UNSPSC-Code:
12352205
NACRES:
NA.79
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Empfohlene Produkte
Biologische Quelle
rice
Qualitätsniveau
Assay
≥75% (GC)
Form
liquid
Farbe
colorless to brown
mp (Schmelzpunkt)
30-31 °C
Lagertemp.
−20°C
SMILES String
O1[C@@](CCc2c1c(c(c(c2C)O)C)C)(CC\C=C(\CC\C=C(\CCC=C(C)C)/C)/C)C
InChI
1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1
InChIKey
RZFHLOLGZPDCHJ-XZXLULOTSA-N
Verwandte Kategorien
Allgemeine Beschreibung
Biochem./physiol. Wirkung
α-Tocotrienol is an effective free radical scavengerand elicits protective functionality during oxidative stress in microsomes.[1] It is a strong antioxidant,[2] which reduces inflammation[4] and is used in cancer treatment.[3] α-tocotrienol supplementation may reduce cholesterol levels in hypercholesterolemia.[3] α-tocotrienol is neuroprotective as it blocks glutamate-induced cell death in neuronal cells.[5]
α-Tocotrienol may be used along with other isoforms to differentiate tocotrienol activities.
Tocotrienols are widely utilized for their strong antioxidant properties. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. α-tocotrienol demonstrates neuroprotective properties by blocking glutamate-induced cell death in neuronal cells.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities
Ramanathan N, et al.
Nutrition & Metabolism, 15(1), 6-6 (2018)
Han-A Park et al.
Stroke, 42(8), 2308-2314 (2011-07-02)
α-Tocotrienol (TCT) represents the most potent neuroprotective form of natural vitamin E that is Generally Recognized As Safe certified by the U.S. Food and Drug Administration. This work addresses a novel molecular mechanism by which α-TCT may be protective against
Savita Khanna et al.
Journal of neurochemistry, 98(5), 1474-1486 (2006-08-23)
The natural vitamin E tocotrienols possess properties not shared by tocopherols. Nanomolar alpha-tocotrienol, not alpha-tocopherol, is potently neuroprotective. On a concentration basis, this finding represents the most potent of all biological functions exhibited by any natural vitamin E molecule. We
Hyunil Ha et al.
Biochemical and biophysical research communications, 406(4), 546-551 (2011-03-01)
Vitamin E, an essential nutrient with powerful antioxidant activity, is the mixture of two classes of compounds, tocopherols (TPs) and tocotrienols (TTs). Although TTs exhibit better bone protective activity than α-TP, the underlying mechanism is poorly understood. In this study
Vladimir Gogvadze et al.
International journal of cancer, 127(8), 1823-1832 (2010-01-28)
Release of mitochondrial proteins such as cytochrome c, AIF, Smac/Diablo etc., plays a crucial role in apoptosis induction. A redox-silent analog of vitamin E, alpha-tocopheryl succinate (alpha-TOS), was shown to stimulate cytochrome c release via production of reactive oxygen species
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what is the source of Tocotrienol rice or rice bran oil
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