SML3426

Glycerol phenylbutyrate

≥95% (HPLC)

• Synonym(e): 1,2,3-Propanetriyl tris(4-phenylbutanoate), GPB, Glyceryl tri-[4-phenylbutyrate, HPN 100, Tri(4-phenylbutyryl)glycerol
• Empirische Formel (Hill-System): C₃₃H₃₈O₆
• CAS-Nummer: 611168-24-2
• Molekulargewicht: 530.65
• MDL-Nummer: MFCD28016960
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: oil
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: O=C(OCC(OC(CCCC1=CC=CC=C1)=O)COC(CCCC2=CC=CC=C2)=O)CCCC3=CC=CC=C3
• InChIKey: ZSDBFLMJVAGKOU-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Glycerol phenylbutyrate, a triacylglycerol, is a prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA). Glycerol phenylbutyrate is a nitrogen-binding agent approved for the chronic management of adult and pediatric patients (≥2 years of age) with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.

Prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA); ammonia scavenger

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable