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Merck

SML0931

Sigma-Aldrich

Carbimazole

≥98% (HPLC)

Synonym(e):

1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline, 1-Methyl-3-carbethoxy-2-thioglyoxalone, 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester, Athyromazole, Carbethoxymethimazole, Carbimazol, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate

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10 MG
46,40 €
50 MG
227,00 €

46,40 €


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10 MG
46,40 €
50 MG
227,00 €

About This Item

Empirische Formel (Hill-System):
C7H10N2O2S
CAS-Nummer:
Molekulargewicht:
186.23
EG-Nummer:
UNSPSC-Code:
12352200
NACRES:
NA.77

46,40 €


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Qualitätsniveau

Assay

≥98% (HPLC)

Form

powder

Farbe

white to beige

Löslichkeit

DMSO: 5 mg/mL, clear (warmed)

Lagertemp.

2-8°C

SMILES String

S=[c]1[n](cc[n]1C(=O)OCC)C

InChI

1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3

InChIKey

CFOYWRHIYXMDOT-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase.
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase. Carbimazole is used to treat hyperthyroidism. Also, carbimazole induces phosphorylation of eukaryotic elongation factor eEF2.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Iodinated contrast-induced thyrotoxicosis.
Paul Dunne et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 185(2), 144-147 (2012-11-14)
E T Bell et al.
The Journal of small animal practice, 53(11), 661-663 (2012-09-11)
A 12-year-old female neutered ragdoll crossbred cat was presented for investigation of generalised weakness and regurgitation. The cat was being treated with transdermal methimazole for hyper-thyroidism, which had been diagnosed 10 weeks previously. An acetylcholine receptor antibody titre was consistent
Franz Ludwig Dumoulin et al.
BMJ case reports, 2012, doi:10-doi:10 (2012-05-19)
A middle aged woman, previously healthy with the exception of mild seasonal asthma was presented with signs of acute hepatitis. The further investigation showed acute hepatitis E virus infection associated with autoimmune thyroiditis. Treatment was started with propranolol and carbimazol
Adoree Yi Ying Lim et al.
Singapore medical journal, 54(7), e133-e136 (2013-08-01)
A 24-year-old Chinese woman with Graves' disease presented with myositis two months after treatment with carbimazole. The patient's myositis resolved with hydration and cessation of carbimazole. No other causes of myositis were found, and a change in the medication to
Kirsten Campbell et al.
Australian family physician, 41(8), 564-572 (2012-11-13)
Thyrotoxicosis is common in the Australian community and is frequently encountered in general practice. Graves disease, toxic multinodular goitre, toxic adenoma and thyroiditis account for most presentations of thyrotoxicosis. This article outlines the clinical presentation and evaluation of a patient

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DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

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