C4024

Carbamazepin

≥98% (HPLC), powder, antiepileptic agent

• Synonym(e): 5H-Dibenz[b,f]azepin-5-carboxamid
• Empirische Formel (Hill-System): C₁₅H₁₂N₂O
• CAS-Nummer: 298-46-4
• Molekulargewicht: 236.27
• EG-Nummer: 206-062-7
• MDL-Nummer: MFCD00005073
• UNSPSC-Code: 12352200
• eCl@ss: 34051404
• PubChem Substanz-ID: 57654002
• NACRES: NA.77

Eigenschaften

• product name: Carbamazepin, powder
• Form: powder
• mp (Schmelzpunkt): 191-192 °C (lit.)
• Löslichkeit: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL; H₂O: insoluble; ethanol: soluble; propylene glycol: soluble
• Ersteller: Novartis
• Lagertemp.: 2-8°C
• SMILES String: NC(=O)N1c2ccccc2C=Cc3ccccc13
• InChI: 1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
• InChIKey: FFGPTBGBLSHEPO-UHFFFAOYSA-N
• Angaben zum Gen: human ... BZRAP1(9256) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , PRNP(5621) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scn2a1(24766) , Scnn1a(25122) , Scnn1g(24768) , Slc6a1(79212)

Beschreibung

Anwendung

Carbamazepine has been used to investigate its behavior in wastewater treatment and during groundwater infiltration. It has also been used to find out its effects on spontaneous seizures in rats.

Biochem./physiol. Wirkung

Carbamazepine is considered as a safe antiepileptic drug. It decreases the multiple drug therapy and maintains a better control of epilepsy.

Antikonvulsivum; Ligand für die Benzodiazepin modulatorische Stelle am GABA_A-Rezeptor; Natriumkanalinhibitor.

Leistungsmerkmale und Vorteile

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H302,H317,H334,H336,H360FD
• P-Sätze: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Repr. 1A - Resp. Sens. 1 - Skin Sens. 1A - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves