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P8374

Sigma-Aldrich

Pyoverdines−Fe complex

from Pseudomonas fluorescens, >90% (HPLC)

Synonym(e):

Pyoverdines, Fe-Pv

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About This Item

UNSPSC-Code:
12352200
NACRES:
NA.32

Biologische Quelle

Pseudomonas fluorescens

Qualitätsniveau

200

Assay

>90% (HPLC)

Form

powder

Löslichkeit

H2O: ~10 mg/mL

Versandbedingung

wet ice

Lagertemp.

−20°C

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Anwendung

Pyoverdines-Fe complex has been used in cyclic voltammetry to determine potential detection windows and peak potentials.

Biochem./physiol. Wirkung

Pyoverdines, also called pseuobactins and pyoverdins, are fluorescent siderophores that have high affinity for iron (1032 M-1), and are synthesized by fluorescent pseudomonads under iron-deficient growth conditions. Pyoverdines were shown to prevent iron toxicity produced by iron overload in hepatocyte cultures and effectively scavenges the hydroxyl and peroxyl radicals. Pyoverdines are effective in acquiring iron from transferrin and lactoferrin. Pyoverdines are also involved in the suppression of pythium-induced damping-off of tomato and promotion of growth in some higher plants.
The complex ferri-pyoverdine acts as a signaling molecule inducing the production of secreted virulence factors in Pseudomonas aeruginosa. Ferri-pyoverdines promote the growth of both P. fluorescens and P. aeruginosa in minimal medium.

Physikalische Form

Supplied as a mixture containing mainly the succinic acid (MW=1161), 2-hydroxy glutaramide (MW=1190), and succinamide (MW=1160) forms of pyoverdines, bound to iron.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
Sensors (2016)
Paul A Beare et al.
Molecular microbiology, 47(1), 195-207 (2002-12-21)
Under iron-limiting conditions, Pseudomonas aeruginosa produces a siderophore called pyoverdine. Pyoverdine is secreted into the extracellular environment where it chelates iron, and the resulting ferri-pyoverdine complexes are transported back into the bacteria by a cell surface receptor protein FpvA. Pyoverdine
Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections
Fatima A
Nanomedicine (London, England) (2016)
Islem Gandouzi et al.
Materials (Basel, Switzerland), 12(7) (2019-04-14)
Pyoverdine is a fluorescent siderophore produced by Pseudomonas aeruginosa that can be considered as a detectable marker in nosocomial infections. The presence of pyoverdine in water can be directly linked to the presence of the P. aeruginosa, thus being a

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