P1034

Phenylisothiocyanat

Sigma Grade, 8.36 M, suitable for solid phase protein sequencing analysis, ≥99% (GC), liquid

• Synonym(e): PITC, Phenylsenföl
• Lineare Formel: C₆H₅NCS
• CAS-Nummer: 103-72-0
• Molekulargewicht: 135.19
• Beilstein: 471392
• EG-Nummer: 203-138-1
• MDL-Nummer: MFCD00004798
• UNSPSC-Code: 12352118
• PubChem Substanz-ID: 24898144
• NACRES: NA.31

Eigenschaften

• Qualität: Sigma Grade
• Qualitätsniveau: 100
• Assay: ≥99% (GC)
• Form: liquid
• Konzentration: 8.36 M
• Brechungsindex: n20/D 1.6515 (lit.)
• bp: 218 °C (lit.)
• mp (Schmelzpunkt): −21 °C (lit.)
• Dichte: 1.132 g/mL at 20 °C (lit.)
• Eignung: suitable for solid phase protein sequencing analysis
• Lagertemp.: 2-8°C
• SMILES String: S=C=Nc1ccccc1
• InChI: 1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H
• InChIKey: QKFJKGMPGYROCL-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Phenyl isothiocyanate belongs to the class of aromatic compounds with isothiocyanate groups. It is typically used as a precolumn derivatization agent for the formation of phenylthiocarbamyl amino acids for their subsequent determination using chromatography techniques.

Anwendung

Phenyl isothiocyanate may be used in the polypeptide and protein sequencing at the subpicomole and subnanomole levels, respectively, by applying automated Edman chemistry followed by the analysis using high-performance liquid chromatography (HPLC) technique.

Derivatisierungsreagens für primäre und sekundäre Amine. Wird gebraucht für die Peptidsequenzierung mittels Edman Abbau und für die Aminosäuren-Analyse mittels HPLC

Verpackung

One mL size packaged in flame sealed amber ampules under argon.
Ten mL size packaged in screw cap amber vials under argon.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05
• Signalwort: Danger
• H-Sätze: H301,H314,H317,H334
• P-Sätze: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 190.4 °F - closed cup
• Flammpunkt (°C): 88 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter