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P0369

Sigma-Aldrich

Anti-Peroxisome Proliferator Activated Receptor α antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-PPARα

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About This Item

MDL-Nummer:
MFCD01092469
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 52 kDa

Speziesreaktivität

mouse

Konzentration

~1 mg/mL

Methode(n)

direct immunofluorescence: 1:100
immunoprecipitation (IP): suitable
western blot: 1 μg/mL

UniProt-Hinterlegungsnummer

P23204

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PPARA(5465)
mouse ... Ppara(19013)

Verwandte Kategorien

Immunogen

synthetic peptide corresponding to residues M(1)VDTESPICPLSPLEADD(18)C of mouse PPARα. The human sequence is 95% (17/18 amino acids) homologous.

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physikalische Form

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Carmen De Caro et al.
Frontiers in pharmacology, 11, 620221-620221 (2021-02-19)
Pain conditions, such as neuropathic pain (NP) and persistent inflammatory pain are therapeutically difficult to manage. Previous studies have shown the involvement of glutamate receptor in pain modulation and in particular same of these showed the key role of the
Claudia Cristiano et al.
Brain, behavior, and immunity, 74, 166-175 (2018-09-09)
Autism spectrum disorders (ASD) are a group of heterogeneous neurodevelopmental conditions characterized by impaired social interaction, and repetitive stereotyped behaviours. Interestingly, functional and inflammatory gastrointestinal diseases are often reported as a comorbidity in ASDs, indicating gut-brain axis as a novel
Maria Bove et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 149, 112820-112820 (2022-03-16)
Drug-naïve psychotic patients show metabolic and hepatic dysfunctions. The rat social isolation model of psychosis allows to investigate mechanisms leading to these disturbances to which oxidative stress crucially contributes. Here, we investigated isolation-induced central and peripheral dysfunctions in glucose homeostasis
Giuseppe D'Agostino et al.
Molecular metabolism, 4(7), 528-536 (2015-07-03)
Nuclear peroxisome proliferator activated receptor-α (PPAR-α) plays a fundamental role in the regulation of lipid homeostasis and is the target of medications used to treat dyslipidemia. However, little is known about the role of PPAR-α in mouse behavior. To investigate
Sangeeta Maity et al.
The Journal of endocrinology, 217(2), 215-228 (2013-02-23)
This study elucidates the role of metabolic remodeling in cardiac dysfunction induced by hyperthyroidism. Cardiac hypertrophy, structural remodeling, and expression of the genes associated with fatty acid metabolism were examined in rats treated with triiodothyronine (T3) alone (8 μg/100 g body weight
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