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N9879

Sigma-Aldrich

NADase from porcine brain

≥0.007 unit/mg solid

Synonym(e):

DPN Nucleosidase, NAD+ glycohydrolase

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5 G
290,00 €

290,00 €


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290,00 €

About This Item

CAS-Nummer:
EC-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.54

290,00 €


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Form

powder

Qualitätsniveau

Spezifische Aktivität

≥0.007 unit/mg solid

Löslichkeit

insoluble

Lagertemp.

−20°C

Allgemeine Beschreibung

NADase is a glycohydrolase that catalyzes ADP-ribose transfer. [1]

Anwendung

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. [2] It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling. [3]

Biochem./physiol. Wirkung

Nicotinamide has been shown to inhibit NADase activity. [4]

Einheitendefinition

One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.

Physikalische Form

Acetone-dried powder

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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D San Segundo et al.
Transplantation proceedings, 44(9), 2676-2678 (2012-11-14)
Posttransplant infection after lung transplantation is a common feature due to the immunodeficiency induced by the immunosuppressive load. To assess B-cell subsets in lung transplant recipients suffering at least one episode of infection within the first year posttransplantation. Twenty-eight lung
H Kim et al.
Molecular and cellular biochemistry, 138(1-2), 237-243 (1994-09-01)
NAD glycohydrolases are the longest known enzymes that catalyze ADP-ribose transfer. The function of these ubiquitous, membrane-bound enzymes has been a long standing puzzle. The NAD glycohydrolases are briefly reviewed in light of the discovery by our laboratory that NAD
Ding-bao Chen et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 607-612 (2012-11-20)
To study the clinical and histopathologic features, diagnosis, pathogenesis and therapy of post-transplant lymphoproliferative disorders (PTLD). The clinical and pathologic features of 15 cases of PTLD were retrospectively analyzed by light microscopy, immunohistochemistry and in-situ hybridization, according to the updated
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Hematology. American Society of Hematology. Education Program, 2012, 76-87 (2012-12-13)
Several prognostic markers based on genetic, phenotypic, and molecular characteristics of chronic lymphocytic leukemia (CLL) B cells have emerged in the past decade. The clinical utility of these newer prognostic indicators, alone or in combination with each other and other
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PloS one, 7(11), e50495-e50495 (2012-12-05)
Hematopoietic stem cells are responsible for the generation of the entire blood system through life. This characteristic relies on their ability to self renew and on their multi-potentiality. Thus quantification of the number of hematopoietic stem cells in a given

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