N4267

α-Neurokinin

≥97% (HPLC)

• Synonym(e): Neurokinin A, Neuromedin L, Substanz K
• Lineare Formel: C₅₀H₇₉N₁₃O₁₅S
• CAS-Nummer: 86933-74-6
• Molekulargewicht: 1133.32
• MDL-Nummer: MFCD00167560
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24897700
• NACRES: NA.32

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥97% (HPLC)
• Form: powder
• Zusammensetzung: Peptide content, ≥70%
• UniProt-Hinterlegungsnummer: P20366
• Lagertemp.: −20°C
• SMILES String: CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc2cnc[nH]2)C(C)O)C(C)C)C(N)=O
• InChI: 1S/C50H80N14O14S/c1-26(2)18-34(45(73)58-32(42(53)70)15-17-79-6)57-38(67)23-55-49(77)40(27(3)4)63-47(75)35(19-29-12-8-7-9-13-29)60-48(76)37(24-65)62-46(74)36(21-39(68)69)61-50(78)41(28(5)66)64-44(72)33(14-10-11-16-51)59-43(71)31(52)20-30-22-54-25-56-30/h7-9,12-13,22,25-28,31-37,40-41,65-66H,10-11,14-21,23-24,51-52H2,1-6H3,(H2,53,70)(H,54,56)(H,55,77)(H,57,67)(H,58,73)(H,59,71)(H,60,76)(H,61,78)(H,62,74)(H,63,75)(H,64,72)(H,68,69)
• InChIKey: HEAUFJZALFKPBA-UHFFFAOYSA-N
• Angaben zum Gen: human ... TAC1(6863)

Beschreibung

Amino Acid Sequence

His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

Allgemeine Beschreibung

Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3.[1][2]

Biochem./physiol. Wirkung

Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro.[3] It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.[1]

Sonstige Hinweise

Lyophilized from 0.1% TFA in H2O

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)