N4143

Neurokinin B

≥95% (HPLC)

• Synonym(e): β-Neurokinin, Neuromedin K
• Empirische Formel (Hill-System): C₅₅H₇₉N₁₃O₁₄S₂
• CAS-Nummer: 86933-75-7
• Molekulargewicht: 1210.42
• MDL-Nummer: MFCD00133665
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24897694
• NACRES: NA.32

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥95% (HPLC)
• Form: powder
• UniProt-Hinterlegungsnummer: Q9UHF0
• Lagertemp.: −20°C
• SMILES String: CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(O)=O)NC(=O)C(Cc3cnc[nH]3)NC(=O)C(CCSC)NC(=O)C(N)CC(O)=O)C(C)C)C(N)=O
• InChI: 1S/C55H79N13O14S2/c1-30(2)21-38(50(77)62-36(47(57)74)17-19-83-5)61-43(69)28-59-55(82)46(31(3)4)68-54(81)40(23-33-15-11-8-12-16-33)65-51(78)39(22-32-13-9-7-10-14-32)64-53(80)42(26-45(72)73)67-52(79)41(24-34-27-58-29-60-34)66-49(76)37(18-20-84-6)63-48(75)35(56)25-44(70)71/h7-16,27,29-31,35-42,46H,17-26,28,56H2,1-6H3,(H2,57,74)(H,58,60)(H,59,82)(H,61,69)(H,62,77)(H,63,75)(H,64,80)(H,65,78)(H,66,76)(H,67,79)(H,68,81)(H,70,71)(H,72,73)
• InChIKey: NHXYSAFTNPANFK-UHFFFAOYSA-N
• Angaben zum Gen: human ... TAC3(6866)

Beschreibung

Amino Acid Sequence

Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2

Biochem./physiol. Wirkung

Neurokinin B is a ten-residue peptide.[1] It is an endogenous tachykinin agonist with preference for the NK-3 receptor.[2][3] It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.[4]

Sonstige Hinweise

Lyophilized from 0.1% TFA in H2O

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)