M2699

Marimastat

≥98% (HPLC), solid, MMP inhibitor

• Synonym(e): BB2516, (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl] propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
• Empirische Formel (Hill-System): C₁₅H₂₉N₃O₅
• CAS-Nummer: 154039-60-8
• Molekulargewicht: 331.41
• MDL-Nummer: MFCD00866242
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329817950
• NACRES: NA.77

Eigenschaften

• Produktbezeichnung: Marimastat, ≥98% (HPLC)
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Löslichkeit: DMSO: ≥20 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C
• InChI: 1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
• InChIKey: OCSMOTCMPXTDND-OUAUKWLOSA-N

Beschreibung

Anwendung

Marimastat has been used as an inhibitor of:

• metalloproteinase 2/9 (MMP2/9), to study its effects on exercise-mediated interleukin-6 (IL-6) release in mice[1]
• metalloproteinase, to determine protease activity in Pseudomonas aeruginosa cultures[2]
• metalloproteinase 10 (MMP10), to study its effect on monoclonal antibody H3 binding to MMP10[3]

Biochem./physiol. Wirkung

Marimastat is a broad spectrum matrix metalloprotease (MMP) inhibitor

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable