SML0041

Batimastat

≥98% (HPLC), powder, matrix metalloproteinase inhibitor

• Synonym(e): BB-94; (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
• Empirische Formel (Hill-System): C₂₃H₃₁N₃O₄S₂
• CAS-Nummer: 130370-60-4
• Molekulargewicht: 477.64
• MDL-Nummer: MFCD00866533
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825111
• NACRES: NA.77

Eigenschaften

• product name: Batimastat, ≥98% (HPLC)
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to tan
• Löslichkeit: DMSO: ≥15 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc2cccs2)C(=O)NO
• InChI: 1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1
• InChIKey: XFILPEOLDIKJHX-QYZOEREBSA-N

Beschreibung

Anwendung

Batimastat has been used to inhibit matrix metalloproteinases (MMPs) activity in various studies.

Biochem./physiol. Wirkung

Batimastat is hydroxamate-type inhibitor of matrix metalloproteinases (MMP). It inhibits the growth and spread of lung tumors, breast cancer regrowth and human colon tumor growth and spread in mouse models. Batimastat reduces MMP-mediated vascular dysfunction and vessel wall damage and enhances the sealing ability and bond strength of dental adhesives.

Batimastat is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable