This product is tested for solubility at 25 mg/mL in 1.4 M NH4OH. According to a published article, this material is also soluble at 50 mg/mL in 1.0 M NaOH. Please see the link below to review this publication:
https://journals.asm.org/doi/10.1128/iai.01924-05
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Wichtige Dokumente
H9039
Hämin
from bovine, ≥90%
Synonym(e):
Chlorhämin, Chloroprotoporphyrin-IX-Eisen(III), Ferriprotoporphyrin-IX-chlorid, Hämin(chlorid)
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1 G
61,60 €
10 G
405,00 €
100 G
860,00 €
About This Item
Empirische Formel (Hill-System):
C34H32ClFeN4O4
CAS-Nummer:
Molekulargewicht:
651.94
Beilstein:
5229914
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352202
PubChem Substanz-ID:
NACRES:
NA.61
Empfohlene Produkte
Biologische Quelle
bovine
Qualitätsniveau
Assay
≥90%
Form
powder
Methode(n)
toxicology assay: suitable
Löslichkeit
1.4 M NH4OH: soluble 25 mg/mL
Lagertemp.
2-8°C
SMILES String
Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C
InChI
1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;
InChIKey
BTIJJDXEELBZFS-HXFTUNQESA-K
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Allgemeine Beschreibung
Heme is a small molecule present either free or bound to hemoglobin in the bloodstream of mammals. This is an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion called hemin. [1]
Anwendung
Hemin was used to study conjugation, characterization and toxicity of lipophosphoglycan-polyacrylic acid conjugate for vaccination against leishmaniasis.[2]
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Hier finden Sie alle aktuellen Versionen:
Analysenzertifikate (COA)
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Kunden haben sich ebenfalls angesehen
Murat Topuzogullari et al.
Journal of biomedical science, 20, 35-35 (2013-06-05)
Research on the conjugates of synthetic polyelectrolytes with antigenic molecules, such as proteins, peptides, or carbohydrates, is an attractive area due to their highly immunogenic character in comparison to classical adjuvants. For example, polyacrylic acid (PAA) is a weak polyelectrolyte
Post-embryonic development in Caenorhabditis elegans.
D L Riddle
International journal for parasitology, 17(1), 223-231 (1987-02-01)
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Reticulon and REEP family of proteins stabilize the high curvature of endoplasmic reticulum (ER) tubules. Plasmodium berghei Yop1 (PbYop1) is a REEP5 homolog in Plasmodium. Here, we characterize its function using a gene-knockout (Pbyop1∆). Pbyop1∆ asexual stage parasites display abnormal
The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans.
Rodgoun Attarian et al.
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The acquisition of iron and the maintenance of iron homeostasis are important aspects of virulence for the pathogenic fungus Cryptococcus neoformans In this study, we characterized the role of the monothiol glutaredoxin Grx4 in iron homeostasis and virulence in C.
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What is the solvent medium, to dissolve hemin stock powder and what is stock concentration of hemin (H9039)
1 Antwort-
Hilfreich?
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What is the recommended method of sterilization in a culture medium with Hemin addition? Autoclaving at 112°C or filter sterilization?
1 Antwort-
Stock solutions of Hemin are typically added to medium and autoclaved at 121 °C for 15-20 minutes. Stock solutions may also be filter sterilized and added aseptically to sterile medium.
Hilfreich?
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I couln´t understand when you say: "There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended." Then for Hemin - from bovine we will not have a Exp.date?
1 Antwort-
A number of products are not included in expiration testing programs, as there is no indication to conclude they are unstable. The only date shown on the certificate of analysis will be the Release Date. For these products there is no stated Retest, Expiration or Use-by-Date Date. We recommend handling per defined conditions as printed in our product literature and website product descriptions. Products should be routinely inspected by the customer to ensure they perform as expected. For those products, only our standard warranty of 1 year from the date of shipment of products is applicable. For further information on our warranty please refer to terms and conditions of sale.
Hilfreich?
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How stable is Hemin, Product H9039, in solution?
1 Antwort-
Sigma-Aldrich has not evaluated the solution stability of hemin solutions. Also, we have not found any information on solution storage in the literature. We recommend that solutions be prepared fresh.
Hilfreich?
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What are some applications for Hemin, Product H9039?
1 Antwort-
Hemin-agarose has reportedly been prepared for use in affinity chromatography of heme-binding proteins. See Tsutsui, K., Affinity chromatography of heme-binding proteins: Synthesis of hemin-agarose. Meth. Enzymol. 123, 331, (1986). Sigma supplies a hemin agarose, product H6390. Hemin can also be used as a component in culture media for the cultivation of bacteria, such as Leishmania tarentolae.
Hilfreich?
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What is the Department of Transportation shipping information for this product?
1 Antwort-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Hilfreich?
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What is the shelf life for Hemin, Product H9039?
1 Antwort-
There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended.
Hilfreich?
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