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Wichtige Dokumente
H6771
2-Hydroxy-tetradecansäure
≥98% (capillary GC)
Synonym(e):
2-Hydroxy-myristinsäure
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About This Item
Empirische Formel (Hill-System):
C14H28O3
CAS-Nummer:
Molekulargewicht:
244.37
Beilstein:
1725369
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352106
PubChem Substanz-ID:
NACRES:
NA.77
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Assay
≥98% (capillary GC)
Lipid-Typ
saturated FAs
Lagertemp.
2-8°C
SMILES String
CCCCCCCCCCCCC(O)C(O)=O
InChI
1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-12-13(15)14(16)17/h13,15H,2-12H2,1H3,(H,16,17)
InChIKey
JYZJYKOZGGEXSX-UHFFFAOYSA-N
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Biochem./physiol. Wirkung
An analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA. Inhibitor of protein myristoylation.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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M S Trent et al.
The Journal of biological chemistry, 276(46), 43122-43131 (2001-09-06)
Attachment of the cationic sugar 4-amino-4-deoxy-l-arabinose (l-Ara4N) to lipid A is required for the maintenance of polymyxin resistance in Escherichia coli and Salmonella typhimurium. The enzymes that synthesize l-Ara4N and transfer it to lipid A have not been identified. We
E B Denner et al.
International journal of systematic and evolutionary microbiology, 51(Pt 3), 827-841 (2001-06-20)
Strain EDIVT, an exopolysaccharide-producing bacterium, was subjected to polyphasic characterization. The bacterium produced copious amounts of an extracellular polysaccharide, forming slimy, viscous, intensely yellow-pigmented colonies on Czapek-Dox (CZD) agar. The culture fluids of the liquid version of CZD medium were
S M Cordo et al.
Microbes and infection, 1(8), 609-614 (1999-12-28)
The effects of two myristic acid analogs on Junin virus (JV) replication were investigated. The compounds chosen for the study were DL-2-hydroxymyristic acid (2OHM), an inhibitor of N-myristoyltransferase (NMT), which binds the enzyme and blocks protein myristoylation, and 13-oxamyristic acid
D R Harper et al.
The Journal of general virology, 74 ( Pt 6), 1181-1184 (1993-06-01)
Inhibitors of myristoylation and analogues of myristic acid inhibit the replication of some retroviruses including human immunodeficiency virus, but no studies with other virus families have been reported. We have shown that replication of varicella-zoster virus (VZV) in tissue is
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