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Merck

H5533

Sigma-Aldrich

Hämin

from bovine, ≥80%

Synonym(e):

Chlorhämin, Chloroprotoporphyrin-IX-Eisen(III), Ferriprotoporphyrin-IX-chlorid, Hämin(chlorid)

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About This Item

Empirische Formel (Hill-System):
C34H32ClFeN4O4
CAS-Nummer:
Molekulargewicht:
651.94
Beilstein:
5229914
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352202
PubChem Substanz-ID:

Biologische Quelle

bovine

Assay

≥80%

Lagertemp.

2-8°C

SMILES String

Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C

InChI

1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChIKey

BTIJJDXEELBZFS-HXFTUNQESA-K

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Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Slide 1 of 3

1 of 3

Bingying Jiang et al.
Biosensors & bioelectronics, 43, 289-292 (2013-01-22)
In this work, we describe the development of a sensitive and label-free aptasensor for thrombin detection based on background noise reduction by exonuclease I (Exo I) and signal amplification by direct electron transfer (DET) of hemin. The thrombin binding aptamers
Dipankar Sen et al.
Critical reviews in biochemistry and molecular biology, 46(6), 478-492 (2011-10-01)
Guanine-rich RNAs and DNAs from chromosomal telomeres and elsewhere that fold into guanine quadruplexes (G-quadruplexes), are found to complex tightly with porphyrins such as N-methylmesoporphyrin IX (NMM) and hemin [Fe(III) heme]. By themselves, these DNAs and RNAs are found to
Takanori Uzawa et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(37), 13859-13864 (2008-09-10)
The earliest steps in the folding of proteins are complete on an extremely rapid time scale that is difficult to access experimentally. We have used rapid-mixing quench-flow methods to extend the time resolution of folding studies on apomyoglobin and elucidate
Dominik J Schaer et al.
Blood, 121(8), 1276-1284 (2012-12-25)
Hemolysis occurs in many hematologic and nonhematologic diseases. Extracellular hemoglobin (Hb) has been found to trigger specific pathophysiologies that are associated with adverse clinical outcomes in patients with hemolysis, such as acute and chronic vascular disease, inflammation, thrombosis, and renal
Stephen R Robinson et al.
Redox report : communications in free radical research, 14(6), 228-235 (2009-12-17)
Hemorrhagic stroke is a common cause of permanent brain damage, with a significant amount of the damage occurring in the weeks following a stroke. This secondary damage is partly due to the toxic effects of hemin, a breakdown product of

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