D4921

Destruxin A from Metarrhizium anisopliae

≥98% (HPLC)

• Empirische Formel (Hill-System): C₂₉H₄₇N₅O₇
• CAS-Nummer: 6686-70-0
• Molekulargewicht: 577.71
• MDL-Nummer: MFCD01736100
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329798802
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: Metarrhizium anisopliae
• Qualitätsniveau: 200
• Assay: ≥98% (HPLC)
• Form: powder
• Lagertemp.: −20°C
• SMILES String: CC[C@H](C)[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CC=C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C1=O
• InChI: 1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)/t18-,19-,20+,21-,23-,24-/m0/s1
• InChIKey: XIYSEKITPHTMJT-UTJJDKHZSA-N

Beschreibung

Anwendung

Destruxin A from Metarrhizium anisopliae has been used for immersion and inoculation bioassay in Rhipicephalus (Boophilus) microplus.[1] It has been used as a transport inhibitor in Drosophila melanogaster.[2]

Biochem./physiol. Wirkung

Destruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects. May suppress the insect immune response.[3] Possesses an inhibitory activity on leukemic cell proliferation, decreasing the number of cells in G₂/M phase.[4] It is virustatic against arboviruses.[5]

Qualität

Balance is other destruxins

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332,H315,H319,H335
• P-Sätze: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves