C9523

Natriumcholesterylsulfat

• Synonym(e): 5-Cholesten-3β-ol-sulfat Natriumsalz, Cholesterin-3-sulfat Natriumsalz, Cholesteryl-sulfat Natriumsalz
• Empirische Formel (Hill-System): C₂₇H₄₅NaO₄S
• CAS-Nummer: 2864-50-8
• Molekulargewicht: 488.70
• Beilstein: 3899884
• MDL-Nummer: MFCD00079091
• UNSPSC-Code: 41141804
• eCl@ss: 39023139
• PubChem Substanz-ID: 24893166
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• Beschreibung: anionic
• Assay: ≥98% (TLC)
• Form: powder
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: [H][C@@]([C@H](C)CCCC(C)C)([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)2[H])[H].[Na+]
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
• InChIKey: LMPVQXVJTZWENW-KPNWGBFJSA-M

Beschreibung

Anwendung

Sodium cholesteryl sulfate was used as the source of cholesterol in the preparation of Edgar′s growth medium used for embryology experiments. It was used as a standard for the separation of human stratum corneum lipids by thin layer chromatography.

Biochem./physiol. Wirkung

Cholesteryl sulfate is a natural constituent of human spermatozoa and has major role in the maturation of sperms. It could also be involved in the capacitation of sperms and enables ovum penetration. Low concentrations of cholesteryl sulfate inhibits acrosin, the proteinase present in sperm acrosome that facilitates ovum penetration.

Angaben zur Herstellung

Sodium cholesteryl sulfate yields clear, colorless solution in chloroform-methanol (1:1) mixture at 10 mg/ml.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)