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B8879

Sigma-Aldrich

Benzethoniumchlorid

≥97% (titration), ≥98% (HPLC)

Synonym(e):

(Diisobutylphenoxyethoxyethyl)dimethylbenzylammoniumchlorid

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Versandbereit am07. April 2025Details


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100 G
77,50 €
250 G
185,00 €
500 G
325,00 €

About This Item

Empirische Formel (Hill-System):
C27H42ClNO2
CAS-Nummer:
Molekulargewicht:
448.08
Beilstein:
3898548
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161900
PubChem Substanz-ID:
NACRES:
NA.25

77,50 €


Versandbereit am07. April 2025Details


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Beschreibung

cationic

Assay

≥97% (titration)
≥98% (HPLC)

Form

powder

Mol-Gew.

448.08 g/mol

mp (Schmelzpunkt)

162-164 °C (lit.)

Löslichkeit

H2O: 100 mg/mL, clear, colorless

Anwendung(en)

microbiology

SMILES String

[Cl-].CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1

InChI

1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1

InChIKey

UREZNYTWGJKWBI-UHFFFAOYSA-M

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Allgemeine Beschreibung

Benzethoniumchlorid ist ein ausführlich charakterisiertes Hautreizmittel und ein seltener Sensibilisator. [1]

Anwendung

Benzethoniumchlorid wurde in einer Studie zur Bewertung der minimalen Hemmkonzentrationen von Methicillin-resistenten Staphylococcus aureus (MRSA-)Isolaten aus Malaysia eingesetzt. [2] Es wurde außerdem in einer Studie zur Untersuchung der Herstellung von Biokompositfolien aus Natriumalginat und modifiziertem Ton verwendet. [3]

Haftungsausschluss

Das Produkt ist nicht für die Verwendung als Biozid gemäß den globalen Biozid-Vorschriften vorgesehen, u. a. dem Federal Insecticide Fungicide and Rodenticide Act der US-amerikanischen EPA, der Europäischen Biozid-Produktverordnung, der kanadischen Behörde für Schädlingsbekämpfung, der türkischen Biozid-Produktverordnung, Koreas Consumer Chemical Products and Biocide Safety Management Act (K-BPR) und andere.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Die Dokumentenbibliothek aufrufen

Michael J Orsini et al.
Journal of medicinal chemistry, 50(3), 462-471 (2007-02-03)
Metastin, also known as KiSS-1, the cognate ligand for the metastin receptor GPR54, is a peptide known to dramatically reduce metastasis in experimental models. Despite this, there is no reported structure for metastin nor any small molecule modulators of metastin
Jacob Pitaro et al.
The Laryngoscope, 123(10), 2521-2525 (2013-08-07)
To determine the ototoxic potential of aluminum acetate (0.5%)/benzethonium chloride (0.03%) otic solution in the chinchilla animal model. A randomized, prospective, controlled study was conducted in the chinchilla animal model. Fourteen female chinchillas were used. After an incision was made
Filiz Tezcan et al.
International journal of biological macromolecules, 50(4), 1165-1168 (2012-01-25)
Sodium alginate/sodium montmorillonite hybrid films were prepared by casting from the suspension of sodium alginate and different clay samples. Clay samples had been modified with a cationic surfactant, a cationic polymer, and a small polar molecule, respectively. Benzethonium chloride, polyethyleneimine
Naoto Kojima et al.
Bioorganic & medicinal chemistry letters, 18(24), 6451-6453 (2008-11-11)
C4-Fluorinated analogues of solamin, an antitumor acetogenin, were synthesized and investigated for their antitumor activities against 39 tumor cell lines. C4-Fluorinated solamins showed more potent growth inhibitory activity against cancer cell lines than solamin.
Elisabeth Lang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 28(2), 347-354 (2011-08-26)
Benzethonium, an antimicrobial surfactant widely used as preservative of pharmaceuticals, topical wound care product and oral disinfectant, triggers apoptosis of several cell types. The apoptosis is preceded and possibly triggered by mitochondrial depolarization. Even though lacking mitochondria, erythrocytes may similarly

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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