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Merck

A4544

Sigma-Aldrich

L-Ascorbinsäure

suitable for cell culture, suitable for plant cell culture, ≥98%

Synonym(e):

L-Threoascorbinsäure, Anti-Scorbut-Faktor, Vitamin C

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About This Item

Empirische Formel (Hill-System):
C6H8O6
CAS-Nummer:
Molekulargewicht:
176.12
Beilstein:
84272
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.21

Qualitätsniveau

Assay

≥98%

Form

powder

Mol-Gew.

Mw 176.12 g/mol

Methode(n)

cell culture | mammalian: suitable
cell culture | plant: suitable

Farbe

white to light yellow

pH-Wert

1.0-2.5 (25 °C, 176 g/L in water)

mp (Schmelzpunkt)

190-194 °C (dec.)

Löslichkeit

water: soluble 50 mg/mL

SMILES String

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChIKey

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Angaben zum Gen

human ... SLC23A2(9962)

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Allgemeine Beschreibung

L-ascorbic acid also called vitamin C, is a water soluble vitamin and acts as a reducing agent for various biochemical reactions. Ascorbic acid plays a key role in the production of collagen. Ascorbic acid is essential for neurodevelopment, neurotransmitter synthesis and modulates neuronal synapsis. Dietary inadequacy of vitamin C has negative impact on cognition.

Anwendung

L-ascorbic acid has been used as an ingredient in the basal medium for bovine mammary epithelial cells and oocyte-granulosa cell complexes. It has been used as a supplement in the osteogenic medium for osteogenic differentiation.

Biochem./physiol. Wirkung

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

The effect of mesenchymal stromal cells on the osseoinduction of impaction grafts
Korda M, et al.
Tissue Engineering: Part A, 16(2), 675-683 (2009)
Multipotency and cardiomyogenic potential of human adipose-derived stem cells from epicardium, pericardium, and omentum
Wystrychowski W, et al.
Stem Cell Research & Therapy, 7(1), 84-84 (2016)
Mitochondrial dysfunction of in vitro grown rabbit oocytes results in preimplantation embryo arrest after activation
Kanaya H, et al.
Journal of Reproduction and Development, 53(3), 631-637 (2007)
Vitamin C status and cognitive function: A systematic review
Travica N, et al.
Nutrients, 9(9), 960-960 (2017)
Does vitamin C deficiency affect cognitive development and function?
Hansen SN, et al.
Nutrients, 6(9), 3818-3846 (2014)

Artikel

Importance and uses of ascorbate in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

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