The half life of this inhibitor has not been determined.
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1 MG
60,40 €
5 MG
241,00 €
60,40 €
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1 MG
60,40 €
5 MG
241,00 €
About This Item
Empirische Formel (Hill-System):
C26H24N2O4
CAS-Nummer:
Molekulargewicht:
428.48
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.77
60,40 €
Auf LagerDetails
Empfohlene Produkte
Biologische Quelle
synthetic (organic)
Qualitätsniveau
Assay
>95% (HPLC)
Form
powder
Mol-Gew.
Mw 428.5
Löslichkeit
DMSO: 10 mg/mL, clear, colorless to greenish-yellow
Lagertemp.
−20°C
SMILES String
N(c2ccc(cc2)c3ccc(cc3)C(=O)[C@H]4[C@@H](CCC4)C(=O)O)C(=O)Nc1ccccc1
InChI
1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23-/m1/s1
InChIKey
BOZRFEQDOFSZBV-DHIUTWEWSA-N
Anwendung
Biochem./physiol. Wirkung
Diacylglycerol acyltransferase (DGAT-1) inhibitor; IC50 7 to 24 nM
The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease. [5]
Physikalische Form
A922500 is supplied as a crystalline solid.
Angaben zur Herstellung
A stock solution may be made by dissolving the A922500 in the solvent of choice. A922500 is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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What is the half life of the inhibitor
1 Antwort-
Hilfreich?
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Hello, in your description sector, it says this product can be dissolved in ethanol. However I have checked other sources that say A922500 is insoluble in ethanol. Could you clarify this for me?
1 Antwort-
This product is tested for solubility in DMSO at 10 mg/mL. The material is less soluble in ethanol at approximately 200 ug/mL. In addition, this compound may be dissolved in dimethylformamide at 20 mg/mL.
Hilfreich?
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