Y0000563

Amitriptylin -hydrochlorid

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): AMT
• Empirische Formel (Hill-System): C₂₀H₂₃N · HCl
• CAS-Nummer: 549-18-8
• Molekulargewicht: 313.86
• MDL-Nummer: MFCD00012537
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329831024
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: amitriptyline
• Hersteller/Markenname: EDQM
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: Cl[H].CN(C)CC\C=C1\c2ccccc2CCc3ccccc13
• InChI: 1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
• InChIKey: KFYRPLNVJVHZGT-UHFFFAOYSA-N
• Angaben zum Gen: human ... SLC6A2(6530) , SLC6A4(6532)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Amitriptyline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with K_is of 100 nM and 14.7 nM, respectively; high in vitro affinity for α₁-adrenoceptors, serotonin and muscarinic acetylcholine receptors.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H301,H319,H361d,H410
• P-Sätze: P201 - P273 - P301 + P310 + P330 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable