A-923

Amitriptyline hydrochloride solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₂₀H₂₄ClN
• CAS-Nummer: 549-18-8
• Molekulargewicht: 313.86
• EG-Nummer: 200-659-6
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Leistungsmerkmale: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• Konzentration: 1.0 mg/mL in methanol
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): clinical testing
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: Cl.CN(C)CC\C=C1\c2ccccc2CCc3ccccc13
• InChI: 1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
• InChIKey: KFYRPLNVJVHZGT-UHFFFAOYSA-N
• Angaben zum Gen: human ... SLC6A2(6530) , SLC6A4(6532)

Beschreibung

Allgemeine Beschreibung

A Certified Spiking Solution^® suitable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, urine drug testing, prescription monitoring or pharmaceutical research. Amitriptyline, marketed as the brand drug Elavil, Tryptizol, or Laroxyl, is a tricyclic antidepressant used in the treatment of major depression, clinical/endogenous depression and involutional melancholia.

Anwendung

• Tricyclic antidepressant research: A study demonstrated the use of antisolvent precipitation to formulate excipient-free nanoparticles of psychotropic drugs, including amitriptyline hydrochloride, which could significantly impact the development of novel drug delivery systems for neuropharmacological applications (Wu and Wang, 2022).


• Neuropharmacology amitriptyline: Research into micellar and interfacial phenomena of amitriptyline hydrochloride with cationic ester-bonded gemini surfactants explored its potential in enhancing drug solubility and stability, which is crucial for neuropharmacological studies and drug delivery systems (Abdul Rub, 2020).


• Amitriptyline liquid formulation: A methodology to create polymeric nanocarriers containing hydrophilic low molecular-weight drugs, such as amitriptyline, offers a green strategy with very high drug loading, facilitating the development of amitriptyline-based formulations for pharmacological research (Villamizar-Sarmiento et al., 2019).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes,Central nervous system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup