PHR1073
Avobenzon
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(e):
1-(4-Methoxyphenyl)-3-(4-tert.-butylphenyl)-1,3-propandion, Butylmethoxydibenzoylmethan
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About This Item
Empirische Formel (Hill-System):
C20H22O3
CAS-Nummer:
Molekulargewicht:
310.39
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24
Empfohlene Produkte
Qualität
certified reference material
pharmaceutical secondary standard
Qualitätsniveau
Agentur
traceable to USP 1045337
API-Familie
avobenzone
Analysenzertifikat (CofA)
current certificate can be downloaded
Methode(n)
HPLC: suitable
gas chromatography (GC): suitable
Anwendung(en)
environmental
pharmaceutical (small molecule)
Format
neat
Lagertemp.
2-30°C
SMILES String
COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C
InChI
1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3
InChIKey
XNEFYCZVKIDDMS-UHFFFAOYSA-N
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Allgemeine Beschreibung
Avobenzone is an active sunscreen ingredient, used in sunscreen lotions and cosmetic formulations.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Anwendung
Avobenzone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Hinweis zur Analyse
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Sonstige Hinweise
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Fußnote
To see an example of a Certificate of Analysis for this material enter LRAB3693 in the slot below. This is an example certificate only and may not be the lot that you receive.
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Robert M Sayre et al.
Photochemistry and photobiology, 81(2), 452-456 (2004-11-25)
A major concern raised about photostability studies of sunscreen products is that the photodegradation of sunscreens does not readily translate into changes in product performance. This study examines the correlation between photochemical degradation of sunscreen agents and changes in protection
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Kerry M Hanson et al.
Journal of cosmetic science, 54(6), 589-598 (2004-01-20)
The ability of sunscreens and antioxidants to deactivate highly destructive reactive oxygen species in human skin has remained inconclusive. Two-photon fluorescence imaging microscopy was used to determine the effect of sunscreen/antioxidant combinations upon UV-induced ROS generation in ex vivo human
Daniele Dondi et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 5(9), 835-843 (2006-10-19)
A systematic investigation of two well-known and popular commercial suncreams reveals significant degradation when exposed to simulated UV sunlight at an irradiance corresponding to natural sunlight. We have examined the photochemistry of two widely used sunscreen active agents in pure
Tatiana Armeni et al.
Toxicology, 203(1-3), 165-178 (2004-09-15)
As an extension of our previous investigations on sunscreen ingredients, the present work was aimed at assessing the possible protective effects of a common UVA-absorbing agent, Parsol 1789 (4-tert-butyl-4'-methoxydibenzoylmethane) in contact with human keratinocytes under UVA illumination. Cell viability was
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