M8277

Midodrin -hydrochlorid

analytical standard, for drug analysis

• Synonym(e): (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol
• Empirische Formel (Hill-System): C₁₂H₁₈N₂O₄ · HCl
• CAS-Nummer: 3092-17-9
• Molekulargewicht: 290.74
• MDL-Nummer: MFCD00079455
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329818055
• NACRES: NA.24

Eigenschaften

• Qualitätsniveau: 100
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• SMILES String: Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
• InChI: 1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
• InChIKey: MGCQZNBCJBRZDT-UHFFFAOYSA-N
• Angaben zum Gen: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

Beschreibung

Allgemeine Beschreibung

Midodrine is a prodrug[1] and a long acting α-adrenergic stimulating agent, and forms an active metabolite, desglymidodrine,[1] which causes an elevation of the systemic blood pressure with the reduction in heart rate.[2]

Anwendung

Midodrine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological samples[2] and pharmaceutical formulations[1] using different chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

α-Adrenerger Agonist; gefässverengendes Mittel

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P301 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges