68923

Aesculetin

analytical standard

• Synonym(e): Aesculetin, 6,7-Dihydroxy-cumarin, Cichorigenin
• Empirische Formel (Hill-System): C₉H₆O₄
• CAS-Nummer: 305-01-1
• Molekulargewicht: 178.14
• Beilstein: 152788
• EG-Nummer: 206-161-5
• MDL-Nummer: MFCD00006874
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329761226
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Assay: ≥97.5% (HPLC); 97.5-102.5% (NT)
• Haltbarkeit: limited shelf life, expiry date on the label
• mp (Schmelzpunkt): 271-273 °C (lit.)
• Format: neat
• SMILES String: Oc1cc2OC(=O)C=Cc2cc1O
• InChI: 1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H
• InChIKey: ILEDWLMCKZNDJK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Esculetin is a derivative of coumarin, found in various plant species including Cichorium intybus (chicory), Bougainvillea spectabilis, Artemisia capillaris, etc and leaves of Citrus limonia (Rutaceae), Ceratostigma willmottianum, etc. It exhibits multiple pharmacological activities and is found to be a potent inhibitor of cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, catechol-O-methyl transferase, NADPH oxidase and xanthine oxidase enzymes.

Anwendung

Esculetin may be used as an analytical reference standard for the determination of the analyte in biological and water samples by chromatography-based techniques. It may also be used as a standard in the quantification of the analyte in traditional herbal medicines by solid-phase extraction and micellar electrokinetic capillary methods, respectively.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable