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Dokumente

93979

Sigma-Aldrich

Umbelliferon

suitable for fluorescence indicator, ≥98.0% (HPLC)

Synonym(e):

7-Hydroxy-2H-1-benzopyran-2-on, 7-Hydroxycumarin

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About This Item

Empirische Formel (Hill-System):
C9H6O3
CAS-Nummer:
93-35-6
Molekulargewicht:
162.14
Beilstein:
127683
EG-Nummer:
202-240-3
MDL-Nummer:
MFCD00006878
UNSPSC-Code:
12171500
PubChem Substanz-ID:
57653583
NACRES:
NA.32

Assay

≥98.0% (HPLC)

Form

crystals

mp (Schmelzpunkt)

230 °C (dec.) (lit.)
230-233 °C

Löslichkeit

dioxane: soluble
ethanol: soluble

Fluoreszenz

λex 325 nm; λem 452 nm in 0.1 M citrate pH 3.0

Eignung

suitable for fluorescence indicator

SMILES String

Oc1ccc2C=CC(=O)Oc2c1

InChI

1S/C9H6O3/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5,10H

InChIKey

ORHBXUUXSCNDEV-UHFFFAOYSA-N

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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Ye V Liu et al.
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In March 2013, diagnosis of the first reported case of human infection with a novel avian-origin influenza A(H7N9) virus occurred in eastern China. Most human cases have resulted in severe respiratory illness and, in some instances, death. Currently there are
Stefan Starcević et al.
Journal of medicinal chemistry, 54(1), 248-261 (2010-12-09)
17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) is an enzyme that catalyzes NADPH-dependent reduction of the weak estrogen, estrone, into the most potent estrogen, estradiol, which exerts proliferative effects via the estrogen receptors. Overexpression of 17β-HSD1 in estrogen-responsive tissues is related to
Kalyan K Sadhu et al.
Organic & biomolecular chemistry, 11(4), 563-568 (2012-10-13)
The design and synthesis of molecular probes competent for pH signaling within or beyond a certain range is a complicated matter. Herein a new mechanism for ''OFF-ON-OFF'' absorbance and fluorescence intensities vs. pH behaviour is described. The probe design is
Juri M Timonen et al.
European journal of medicinal chemistry, 46(9), 3845-3850 (2011-06-18)
A number of 7-hydroxycoumarins have been synthesised by Pechmann cyclisation using differently substituted resorcinols employing perchloric acid as the condensing agent. All the compounds have been characterised by analytical and spectroscopic methods. The anti-inflammatory properties were tested with LPS-induced inflammation
Hiromu Kashida et al.
Bioorganic & medicinal chemistry, 20(14), 4310-4315 (2012-06-19)
In this study, we synthesized a simple but efficient quencher-free molecular beacon tethering 7-hydroxycoumarin on D-threoninol based on its pK(a) change. The pK(a) of 7-hydroxycoumarin in a single strand was determined as 8.8, whereas that intercalated in the duplex was
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