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ABD12

Sigma-Aldrich

Anti-Aldehyde dehydrogenase 1 (ALDH1A1) Antibody

from rabbit, purified by affinity chromatography

Synonym(e):

aldehyde dehydrogenase 1 family, member A1, ALDH class 1, Aldehyde dehydrogenase, cytosolic, retinaldehyde dehydrogenase 1, Aldehyde dehydrogenase family 1 member A1, retinal dehydrogenase 1, acetaldehyde dehydrogenase 1, aldehyde dehydrogenase 1, solubl

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

human

Verpackung

antibody small pack of 25 μg

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

ambient

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ALDH1A1(216)

Allgemeine Beschreibung

Aldehyde dehydrogenase 1A1 (ALDH1A1) is also known as retinal dehydrogenase 1. It is thought to be a main converter of retinol to retinoic acid, which is very important in cell to cell signaling. ALDH1A1 may also be involved in inhibiting invasion in pancreatic cancer cells. More specifically, ALDH1A1 may regulate hematopoietic stem cell differentiation by disrupting the retinoid signaling.

Spezifität

Other homologies: rat and mouse (91% sequence homology).

Immunogen

KLH-conjugated linear peptide corresponding to human Aldehyde dehydrogenase 1.

Anwendung

Research Category
Stammzellforschung
This Anti-Aldehyde dehydrogenase 1 (ALDH1A1) Antibody is validated for use in WB for the detection of Aldehyde dehydrogenase 1 (ALDH1A1).

Qualität

Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 0.05 µg/mL of this antibody detected Aldehyde dehydrogenase 1 on 10 µg of HepG2 cell lysate.

Zielbeschreibung

~54 kDa observed

Physikalische Form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
HepG2 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Empfehlung

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Natalia Ninkina et al.
Neurobiology of aging, 91, 76-87 (2020-04-01)
The etiology and pathogenesis of Parkinson's disease (PD) are tightly linked to the gain-of-function of α-synuclein. However, gradual accumulation of α-synuclein aggregates in dopaminergic neurons of substantia nigra pars compacta (SNpc) leads to the depletion of the functional pool of
Yi Sui et al.
Annals of translational medicine, 9(1), 45-45 (2021-02-09)
Prostate cancer (PCa) is one of the most common types of cancer and the emerging resistance to androgen deprivation therapy in PCa aggravates disease progression. In this study, we examined the potential pro-tumorigenic functions of NANOGP8 in prostate cancer development.
Yi Sui et al.
British journal of cancer, 125(7), 1003-1015 (2021-07-12)
Metastasis is the major cause of treatment failure and cancer-related deaths in prostate cancer (PCa) patients. Our previous study demonstrated that a CD44+ subpopulation isolated from PCa cells or tumours possesses both stem cell properties and metastatic potential, serving as
Angelica R Harper et al.
PloS one, 10(3), e0122008-e0122008 (2015-03-21)
Retinaldehyde dehydrogenase 2 (RALDH2) has been implicated in regulating all-trans-retinoic acid (atRA) synthesis in response to visual signals in animal models of myopia. To explore the potential role of retinaldehyde dehydrogenase (RALDH) enzymes and atRA in human postnatal ocular growth

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