Direkt zum Inhalt
Merck
Alle Fotos(1)

Wichtige Dokumente

Gesamtdokumentation anzeigen

880680P

Avanti

C16 PEG750 Ceramide

Avanti Research™ - A Croda Brand 880680P, powder

Synonym(e):

N-palmitoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)750]}

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

25 MG
458,00 €

458,00 €

Auf LagerDetails

Bulk-Bestellung anfordern
Alle Fotos(1)

Größe auswählen

Ansicht ändern
25 MG
458,00 €

About This Item

CAS-Nummer:
212116-78-4
UNSPSC-Code:
12352211
NACRES:
NA.25

458,00 €

Auf LagerDetails

Bulk-Bestellung anfordern

Form

powder

Verpackung

pkg of 1 × 25 mg (880680P-25mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 880680P

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

O=C(CCC(OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC)=O)OOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC.C=C

InChIKey

PZQTVIDFPGJTMH-TWVCMLEGSA-N

Allgemeine Beschreibung

Ceramide is a sphingolipid metabolite. The ceramides differ in their acyl chain length.[1]

Anwendung

C16 PEG750 Ceramide might be used as a control to test for nonspecific interactions during titrations of DNA-nanotube complexes with polyethylene glycol (PEG)-conjugated lipids.[2]

Biochem./physiol. Wirkung

Therapeutic drugs enclosed in poly-ethylene glycol (PEG) conjugated ceramide serves as liposomal carriers, ensuring a longer circulation period. It exhibits a neutral surface electrostatic charge which prevents the leaking of positively charged encapsulated drug molecule.[3]

Verpackung

5 mL Amber Glass Screw Cap Vial (880680P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumente section.

Wenn Sie Hilfe benötigen, wenden Sie sich bitte an Kundensupport

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

M S Webb et al.
Biochimica et biophysica acta, 1372(2), 272-282 (1998-07-24)
Poly(ethylene glycol) (PEG) conjugated lipids have been used to increase the circulation longevity of liposomal carriers encapsulating therapeutic compounds. PEG is typically conjugated to distearoylphosphatidylethanolamine (DSPE) via a carbamate linkage that results in a net negative charge on the phosphate
Prakrit V Jena et al.
ACS nano, 11(11), 10689-10703 (2017-09-13)
Lipid accumulation within the lumen of endolysosomal vesicles is observed in various pathologies including atherosclerosis, liver disease, neurological disorders, lysosomal storage disorders, and cancer. Current methods cannot measure lipid flux specifically within the lysosomal lumen of live cells. We developed
Jamie L Betker et al.
Journal of pharmaceutical sciences (2020-02-01)
Nanoparticle-mediated drug delivery has long utilized PEGylation as a mechanism for reducing uptake by the reticuloendothelial system and extending circulation lifetimes. However, studies over the past 2 decades have established that immune responses to PEG can promote clearance on repeat injection
Michal Levy et al.
IUBMB life, 62(5), 347-356 (2010-03-12)
In mammals, ceramide, a key intermediate in sphingolipid metabolism and an important signaling molecule, is synthesized by a family of six ceramide synthases (CerS), each of which synthesizes ceramides with distinct acyl chain lengths. There are a number of common

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.