810611P

CNO

Avanti Research^™ - A Croda Brand

• Synonym(e): 25-doxyl-cholesterol
• Empirische Formel (Hill-System): C₃₀H₅₀NO₃
• CAS-Nummer: 109024-15-9
• Molekulargewicht: 472.72
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: powder
• Zusammensetzung: (contains 10-15% of the ring-opened ketone, TLC)
• Verpackung: pkg of 1 × 1 mg (810611P-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Lipid-Typ: ESR probes; ESR probes
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@](CC[C@]1([C@](CC=C2C[C@H](CC[C@]32C)O)4[H])[H])([C@]1(CC[C@@]43[H])C)[C@H](C)CCCC5(OCC(C)(C)N5[O])C
• InChI: 1S/C30H50NO3/c1-20(8-7-15-30(6)31(33)27(2,3)19-34-30)24-11-12-25-23-10-9-21-18-22(32)13-16-28(21,4)26(23)14-17-29(24,25)5/h9,20,22-26,32H,7-8,10-19H2,1-6H3/t20-,22+,23?,24-,25?,26?,28+,29-,30?/m1/s1
• InChIKey: VPKXVMQRURBFJA-AQHLAHBHSA-N

Beschreibung

Allgemeine Beschreibung

A new paramagnetic analogue of cholesterol as a tool for studying molecular interactions of genuine cholesterol.

Anwendung

CNO (25-doxyl-cholesterol) has been used in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes reconstituted with mammalian translocator protein (mTSPO) (mTSPO:DMPC molar ratio of 1:20) for nuclear magnetic resonance (NMR) experiments.[1]

CNO has been used to study the interactions of membrane proteins with cholesterol.[2]

Biochem./physiol. Wirkung

CNO (25-doxyl-cholesterol) is an analog for native cholesterol. It is used in the preparation of multilamellar vesicles.[3] It is used as a spin-labelled analog of cholesterol.[4]

Verpackung

5 mL Amber Glass Screw Cap Vial (810611P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids