748854

Iodotrimethylsilane solution

1 M in dichloromethane

• Synonym(e): Iodotrimethylsilane solution, TMS iodine, TMS-I, TMSI, Trimethyliodosilane
• Empirische Formel (Hill-System): C₃H₉ISi
• Molekulargewicht: 200.09
• UNSPSC-Code: 12352101
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Konzentration: 1 M in dichloromethane
• Brechungsindex: n20/D 1.433
• Dichte: 1.334 g/mL at 25 °C
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

Iodotrimethylsilane [(CH₃)₃SiI] is an important and versatile organosilicon reagent with wide applications in organic synthesis. It is used as a neutral nucleophilic reagent, trimethylsilylating agent, Lewis acid catalyst, reducing agent and dehydrating agent in many organic reactions.

Anwendung

Iodotrimethylsilane can be used as:

• A reagent in the hydroiodation of ynamides to yield the important building blocks (E)-α-iodoenamides.
• A reagent in the synthesis of (1-iodovinyl) arenes by hydroiodation of trimethylsilyl ethynylarenes.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H225,H314,H336,H351
• P-Sätze: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• Zielorgane: Central nervous system
• Zusätzliche Gefahrenhinweise: EUH014
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): -23.8 °F
• Flammpunkt (°C): -31 °C