720429

1H-Pyrazol-3-ylboronsäure Hydrat

• Empirische Formel (Hill-System): C₃H₅BN₂O₂ · xH₂O
• Molekulargewicht: 111.90 (anhydrous basis)
• MDL-Nummer: MFCD11044442
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 329763716
• NACRES: NA.22

Eigenschaften

• Form: solid
• mp (Schmelzpunkt): 88-93 °C
• Lagertemp.: 2-8°C
• SMILES String: O.OB(O)c1cc[nH]n1
• InChI: 1S/C3H5BN2O2.H2O/c7-4(8)3-1-2-5-6-3;/h1-2,7-8H,(H,5,6);1H2
• InChIKey: NXQCQMBEFQLICU-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1H-Pyrazol-3-ylboronic acid hydrate can be used as a reactant in the Suzuki-Miyaura coupling reaction to synthesize pyrazole derivatives by reacting with different aryl halides over the palladium catalyst.[1]

Anwendung

Reactant for:

• Preparation of receiver-amplifier, self-immolative dendrimers as potential platform for self-triggered multiple-release prodrugs
• Preparation of bifunctional water-soluble triazole-containing derivatives of ethyl(hydroxycamptothecin) via click chemistry and conjugation to monoclonal antibodies for anticancer therapy

• Intermediate for synthesis of oligo(ethylene glycol)-terminated alkanethiol amides useful for biosensors

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable