683906

2-Acetamidophenylboronsäure

≥95%

• Synonym(e): 2-Carbamoylbenzolboronsäure
• Lineare Formel: (CH₃CONH)C₆H₄B(OH)₂
• CAS-Nummer: 169760-16-1
• Molekulargewicht: 178.98
• MDL-Nummer: MFCD02179474
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24885788
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: solid
• mp (Schmelzpunkt): >300 °C
• Funktionelle Gruppe: amide
• Lagertemp.: 2-8°C
• SMILES String: CC(=O)Nc1ccccc1B(O)O
• InChI: 1S/C8H10BNO3/c1-6(11)10-8-5-3-2-4-7(8)9(12)13/h2-5,12-13H,1H3,(H,10,11)
• InChIKey: UMOPBIVXPOETPG-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

May contain varying amounts of anhydride.

Anwendung

Reactant for preparation of:

• Highly substituted acenes via rhodium-catalyzed oxidative coupling with alkynes
• Anticancer pyrimidines with multiple-kinase inhibitory effect
• 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors
• Polycyclic azaindoles as JAK2 inhibitors
• ROS1 receptor tyrosine kinase inhibitors
• 2-aminopyrazolopyridines as Polo-like kinase 1 inhibitors

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)