637513

(S)-(+)-3-Fluorpyrrolidinhydrochlorid

97%

• Synonym(e): (3S)-(+)-3-Fluoropyrrolidine hydrochloride, (3S)-3-Fluoropyrrolidine hydrochloride
• Empirische Formel (Hill-System): C₄H₈FN · HCl
• CAS-Nummer: 136725-53-6
• Molekulargewicht: 125.57
• MDL-Nummer: MFCD04038718
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24882861
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• Optische Aktivität: [α]20/D +8°, c = 1% in methanol
• mp (Schmelzpunkt): 183-187 °C (lit.)
• Funktionelle Gruppe: fluoro
• SMILES String: Cl.F[C@H]1CCNC1
• InChI: 1S/C4H8FN.ClH/c5-4-1-2-6-3-4;/h4,6H,1-3H2;1H/t4-;/m0./s1
• InChIKey: LENYOXXELREKGZ-WCCKRBBISA-N

Beschreibung

Anwendung

(S)-(+)-3-Fluoropyrrolidine hydrochloride can be employed as a building block for the preparation of:

• Fluorinated pyrrolidine derivatives of cyclohexylglycine amides as potential inhibitors for dipeptidyl peptidase IV.[1]
• Fluoropyrrolidine contaning N--ethylurea pyrazole derivatives as potential and selective inhibitors for Trypanosoma brucei and Trypanosoma cruzi parasitic causative agents.[2]
• Urea derivatives of (S)-2-(3,4-difluorophenyl)-5-(3-fluoro-N-pyrrolidylamido)benzothiazole as potent antitrypanosomal agents.[3]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves