52927

(S)-3-(Boc-amino)-pyrrolidin

≥98.0% (TLC)

• Synonym(e): (S)-3-Pyrrolidinylcarbamidsäure-tert-butylester
• Empirische Formel (Hill-System): C₉H₁₈N₂O₂
• CAS-Nummer: 122536-76-9
• Molekulargewicht: 186.25
• Beilstein: 5377813
• MDL-Nummer: MFCD00143194
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 57651390
• NACRES: NA.22

Eigenschaften

• Assay: ≥98.0% (TLC)
• Form: solid
• Optische Aktivität: [α]/D -21.5±2.0°, c = 1 in ethanol
• SMILES String: CC(C)(C)OC(=O)N[C@H]1CCNC1
• InChI: 1S/C9H18N2O2/c1-9(2,3)13-8(12)11-7-4-5-10-6-7/h7,10H,4-6H2,1-3H3,(H,11,12)/t7-/m0/s1
• InChIKey: DQQJBEAXSOOCPG-ZETCQYMHSA-N

Beschreibung

Anwendung

(S)-3-(Boc-amino)pyrrolidine can be used as a building block to prepare:

• 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as potent inhibitors against EGFR tyrosine kinase.
• Aminopyrrolidine scaffolds for asymmetric Morita−Baylis-Hillman reaction.
• N-benzyl-3-sulfonamidopyrrolidines as potent bacterial cell division inhibitors.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves