425761

4-tert-Butylphenol

purified by sublimation, 99%

• Lineare Formel: (CH₃)₃CC₆H₄OH
• CAS-Nummer: 98-54-4
• Molekulargewicht: 150.22
• Beilstein: 1817334
• EG-Nummer: 202-679-0
• MDL-Nummer: MFCD00002367
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24866665
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 1 mmHg ( 70 °C)
• Assay: 99%
• Aufgereinigt durch: sublimation
• bp: 236-238 °C (lit.)
• mp (Schmelzpunkt): 96-101 °C (lit.)
• Dichte: 0.908 g/mL at 25 °C (lit.)
• SMILES String: CC(C)(C)c1ccc(O)cc1
• InChI: 1S/C10H14O/c1-10(2,3)8-4-6-9(11)7-5-8/h4-7,11H,1-3H3
• InChIKey: QHPQWRBYOIRBIT-UHFFFAOYSA-N
• Angaben zum Gen: mouse ... Esr1(13982) ; rat ... Ar(24208)

Beschreibung

Allgemeine Beschreibung

4-tert-Butylphenol (t-BP, 4-TBP, p-tert-butylphenol, PTBP) is an alkyl phenol. It is an aquatic pollutant and an endocrine disrupting chemical (EDC).[1] Exposure to 4-TBP is reported to be one of the factors causing vitiligo.[2][3] Its genotoxic potential has been studied by in vivo micronucleus tests in a category approach.[4] The degradation of t-BP in water using UV/micro-aeration process has been investigated.[5] Methods for its determination in water[6] and cereal samples have been reported.[7] The kinetics of chlorination reaction of 4-tert-butylphenol in aqua has been studied.[8] The hydrogenation of PTBP to form cis-4-tert-butylcyclohexanol (PTBCH) with high selectivity in the presence of supported rhodium catalyst has been reported.[9][10] The effect of UV and combined MW–UV irradiation on 4-TBP transformation has been studied.[11]

Anwendung

4-tert-Butylphenol may be used as a sole carbon source for Sphingobium fuliginis strains isolated from rhizosphere sediment of the reed Phragmites australis.[1] It may be used as a precursor to synthesize 4-fluorophenols.[12]

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H315,H318,H361f,H410
• P-Sätze: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves