385530

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)-uroniumtetrafluoroborat

97%, for peptide synthesis

• Synonym(e): O-(N-Succinimidyl)-N,N,N′,N′-tetramethyluronium-tetrafluoroborat, TSTU
• Empirische Formel (Hill-System): C₉H₁₆BF₄N₃O₃
• CAS-Nummer: 105832-38-0
• Molekulargewicht: 301.05
• MDL-Nummer: MFCD00077875
• UNSPSC-Code: 12352107
• PubChem Substanz-ID: 24864036
• NACRES: NA.22

Eigenschaften

• product name: N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)-uroniumtetrafluoroborat, 97%
• Assay: 97%
• Eignung der Reaktion: reaction type: Coupling Reactions
• mp (Schmelzpunkt): 198-201 °C (lit.)
• Anwendung(en): peptide synthesis
• Lagertemp.: 2-8°C
• SMILES String: F[B-](F)(F)F.CN(C)C(\ON1C(=O)CCC1=O)=[N+](\C)C
• InChI: 1S/C9H16N3O3.BF4/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;2-1(3,4)5/h5-6H2,1-4H3;/q+1;-1
• InChIKey: YEBLHMRPZHNTEK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate is commonly used for the conversion of carboxylic acid into the corresponding N-hydroxysuccinimidyl (NHS) ester.

Anwendung

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate may be used in the synthesis of N-succinimidyl 4-[¹⁸F]fluorobenzoate ([¹⁸F]SFB), a ¹⁸F-labeled agent used for labeling biomarkers. it may also be used for the activation of carboxylic group of C16-chained alkanethiols that are used in developing surface plasmon resonance (SPR) sensors.

Reactant for:
Linking sensor molecules with amino groups to amino functionalized AFM tips

Reactant for synthesis of:
A polymer supported oranotin reagent for prosthetic group labeling of biological macromolecules with radioiodine
L-Rhamnose antigen
Fluorinated rhodamines for optical microscopy and nanoscopy
c(RGDyK) targeted SN38 prodrug
Polyelectrolytes for thin film construction

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1A
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves