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226289

Sigma-Aldrich

N,N-Dimethyltrimethylsilylamin

97%

Synonym(e):

N-(Trimethylsilyl)-dimethylamin, Dimethylaminotrimethylsilan, TMSDMA

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10 G
45,50 €
50 G
188,00 €

About This Item

Lineare Formel:
(CH3)3SiN(CH3)2
CAS-Nummer:
Molekulargewicht:
117.26
Beilstein:
1731861
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

45,50 €


Versandbereit am22. April 2025Details


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Qualitätsniveau

Assay

97%

Form

liquid

Brechungsindex

n20/D 1.397 (lit.)

bp

84 °C (lit.)

Dichte

0.732 g/mL at 25 °C (lit.)

Funktionelle Gruppe

amine

SMILES String

CN(C)[Si](C)(C)C

InChI

1S/C5H15NSi/c1-6(2)7(3,4)5/h1-5H3

InChIKey

KAHVZNKZQFSBFW-UHFFFAOYSA-N

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Anwendung

N,N-Dimethyltrimethylsilylamine can be used as a reactant to prepare:
  • Trifluoromethylacetophenone-N,N-dimethyltrimethylsilylamine adduct, which is used as an efficient reagent for nucleophilic trifluoromethylation of carbonyl and the imine group.[1]
  • (Dimethylamino)sulfur trifluoride (Me-DAST), which is employed as a deoxofluorinating agent for the conversion of aliphatic alcohols into their corresponding fluorides.[2]
  • Nucleoside phosphoramidites by reacting with alkyloxy (or aryloxy)-triazolylphosphine and deoxynucleoside.[3]

It can also be used as a silylating agent in chemical synthesis.[4]

Zubehör

Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

FlameCorrosion

Signalwort

Danger

Gefahreneinstufungen

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - Water-react 1

Lagerklassenschlüssel

4.3 - Hazardous materials which set free flammable gases upon contact with water

WGK

WGK 3

Flammpunkt (°F)

10.4 °F - closed cup

Flammpunkt (°C)

-12 °C - closed cup

Persönliche Schutzausrüstung

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Synthesis and evaluation of novel daunomycin-phosphate-sulfate-β-glucuronide and-β-glucoside prodrugs for application in ADEPT
Leenders, Ruben GG, et al.
Bioorganic & medicinal chemistry letters, 5(24), 2975-2980 (1995)
A new and general procedure for the preparation of deoxynucleoside phosphoramidites.
Fourrey JL and Varenne J.
Tetrahedron Letters, 24(19), 1963-1966 (1983)
Tetrahedron, 49, 2299-2299 (1993)
Tetrahedron Letters, 34, 5863-5863 (1993)
J. Photopolym. Sci. Technol., 5, 123-123 (1992)

Artikel

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Fragen

1-2 von 2 Fragen  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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