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Sigma-Aldrich

Oxonsäure Kaliumsalz

97%

Synonym(e):

4,6-Dihydroxy-1,3,5-triazin-2-carbonsäure Kaliumsalz, Allantoxansäure

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5 G
31,70 €
25 G
152,00 €
100 G
420,00 €

31,70 €

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5 G
31,70 €
25 G
152,00 €
100 G
420,00 €

About This Item

Empirische Formel (Hill-System):
C4H2KN3O4
CAS-Nummer:
2207-75-2
Molekulargewicht:
195.17
EG-Nummer:
218-627-5
MDL-Nummer:
MFCD00010565
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24849591
NACRES:
NA.22

31,70 €

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Qualitätsniveau

200

Assay

97%

mp (Schmelzpunkt)

300 °C (lit.)

SMILES String

[K+].[O-]C(=O)C1=NC(=O)NC(=O)N1

InChI

1S/C4H3N3O4.K/c8-2(9)1-5-3(10)7-4(11)6-1;/h(H,8,9)(H2,5,6,7,10,11);/q;+1/p-1

InChIKey

IAPCTXZQXAVYNG-UHFFFAOYSA-M

Verwandte Kategorien

Anwendung

Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.[1] It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.[2]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCJ1439
BCCG6675
STBJ5376
STBH8632
STBH0976

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The Journal of pharmacy and pharmacology, 70(1), 124-132 (2017-10-24)
Traditional Chinese herbal formulas are difficult to be understood because of complex compositions and specific therapeutic principles. To better understand herbal compatibility in Traditional Chinese medicine (TCM), this study was conducted to investigate the effects of a Chinese pharmacopoeia-listed formula
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PloS one, 14(4), e0214862-e0214862 (2019-04-06)
The effects of hyperuricemia on the expression of kidney drug transporters and on the pharmacokinetics of several substrate drugs were examined. We first established a rat model of hyperuricemia without marked symptoms of chronic kidney failure by 10-day co-administration of
T Shirasaka et al.
Cancer research, 53(17), 4004-4009 (1993-09-01)
The possibility of decreasing the gastrointestinal (GI) toxic effects of 5-fluorouracil (5-FU) on the digestive tract such as its injury of cells and induction of diarrhea, without reducing its antitumor activity, was investigated in rats. Oxonic acid was found to
Yasushi Habu et al.
Biochemical pharmacology, 69(6), 993-999 (2005-03-08)
We previously reported that in hyperuricemic rats, renal impairment occurred and organic ion transport activity decreased, accompanied with a specific decrease in the expression of rat organic anion transporters, rOAT1 and rOAT3, and organic cation transporter, rOCT2. In the present
Haruka Fujikawa et al.
Antioxidants (Basel, Switzerland), 9(5) (2020-05-10)
The oxidant/antioxidant imbalance plays a pivotal role in the lung. Uric acid (UA), an endogenous antioxidant, is highly present in lung tissue, however, its impact on lung function under pathophysiological conditions remains unknown. In this work, pharmacological and genetic inhibition
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Fragen

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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