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HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Synonyme:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Buspiron -hydrochlorid, ,
Spezies
human
(R)-(+)-8-Hydroxy-DPAT hydrobromide, ≥98% (HPLC), solid,
Spezies
human
Buspiron -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Buspiron-Hydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
DCEBIO, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
WAY-100635 -maleat (Salz), powder,
Spezies
human
1-(3-Methoxyphenyl)piperazin, 95%,
Spezies
rat
GR 103691, ≥98% (HPLC), solid,
Spezies
rat
1-(4-Methoxyphenyl)piperazin, 97%,
Spezies
mouse, rat
Alverin -citrat (Salz), ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Serotonin in Kaninchen hergestellte Antikörper, whole antiserum,
Speziesreaktivität
human, rat
Anwendung
immunohistochemistry
Anti-Serotonin Antibody, clone YC5/45, culture supernatant, clone YC5/45, Chemicon®,
Speziesreaktivität
human, lizard, mouse, pig, rabbit, rat
Anwendung
immunohistochemistry
Anti-Serotonin Receptor 1A Antibody, serum, Chemicon®,
Speziesreaktivität
rat
Anwendung
immunohistochemistry
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-5HT1A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Trazodon -hydrochlorid, ≥99% (HPLC), powder,
Spezies
human
(S)-(−)-Propranolol -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
Trimipramin -maleat (Salz), ≥98% (TLC), powder,
Spezies
human
Zimelidin -dihydrochlorid, solid,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Vilazodone hydrochloride, ≥98% (HPLC),
Spezies
human
1,2,3,4-Tetrahydroisoquinolin, 95%,
Spezies
rat, human
Trazodon -hydrochlorid, ≥99% (HPLC), powder,
Spezies
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Spezies
human
R-(−)-Fluoxetin -hydrochlorid, >98% (HPLC), solid,
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
5-Hydroxyindol-3-Essigsäure, ≥98% (HPLC), crystalline,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
BP897, >98% (HPLC), solid,
Spezies
human, rat
Mifepriston, ≥98%,
Spezies
human, mouse, rat
Haloperidol, powder,
Spezies
human, rat
Clozapin, ,
Spezies
human, rat

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
5-Hydroxy-L-Tryptophan, powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human HTR1A,
Spezies
human