Direkt zum Inhalt
Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonyme:
EPND, GluN2A, NMDAR2A, NR2A
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
1,4-Bis(3-aminopropyl)piperazin, ≥99%,
Spezies
rat
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Spezies
human
Dextromethorphan -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Dextromethorphan, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Dextromethorphan -hydrobromid, meets USP testing specifications,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
4-Aminopiperidin, ,
Spezies
rat
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
(±)-Ketamin -hydrochlorid, solid,
Spezies
human
S-(+)-Ketamine hydrochloride, ,
Spezies
human
Ketamin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Glycin, ReagentPlus®, ≥99% (HPLC),
Spezies
rat
Glycin, suitable for electrophoresis, ≥99%,
Spezies
rat
Glycin, BioUltra, for molecular biology, ≥99.0% (NT),
Spezies
rat
Glycin, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Spezies
rat
Glycin, ,
Spezies
rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-NR2A-Antikörper, Klon A12W, Kaninchen, monoklonal, culture supernatant, clone A12W, Upstate®,
Speziesreaktivität
mouse, rat
Anwendung
western blot
Anti-NMDAR2A-Antikörper, Chemicon®, from rabbit,
Speziesreaktivität
fish, human, mouse, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-NR2A-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
mouse, rat
Anwendung
immunoprecipitation (IP)
western blot
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho NMDAR2A (Ser1459), ,
Speziesreaktivität
human
Anwendung
immunocytochemistry
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Spezies
human
Agmatin -sulfat (Salz), ≥97%, powder,
Spezies
human
Orphenadrin -hydrochlorid, ≥98.0% (AT),
Spezies
human
Orphenadrin für die Peakidentifizierung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Orphenadrin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Indol-2-Carboxylsäure, 98%,
Spezies
rat, human
1,3-Diphenylguanidin, 97%,
Spezies
rat, mouse, human
Quisqualinsäure, powder,
Spezies
rat
Nω-Nitro-L-Arginin, ≥98% (TLC),
Spezies
rat, mouse, human
Pentamidin Isethionatsalz, powder,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
1,3-Diaminopropan, ≥99%,
Spezies
rat
N,N′-Dimethyl-1,3-propandiamin, 97%,
Spezies
rat
N,N,N′,N′-Tetramethyl-1,3-propandiamin, ≥99%,
Spezies
rat
1,3-Diamino-2-propanol, 95%,
Spezies
rat
2,2-Dimethyl-1,3-propandiamin, 99%,
Spezies
rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GRIN2A,
Spezies
human
MISSION® esiRNA, targeting mouse Grin2a,
Spezies
mouse